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Genetics

·December 6, 2023·5 min read

Cellular Atlas of Human Limb Development Created

Scientists have created a groundbreaking spatial cell atlas of the human limb, capturing the intricate process of human limb development. This work, part of the Human Cell Atlas initiative, marks a significant advancement in understanding the rapid and complex formation of human limbs.

Featured Genetics Neurology Neuroscience

·December 6, 2023·5 min read

Key Protein in Frontotemporal Dementia Uncovered

The protein TAF15 is responsible for certain cases of frontotemporal dementia. Previously, the protein causing this type of dementia remained unidentified in about 10% of cases.

Featured Genetics Neurology Neuroscience

·December 5, 2023·3 min read

Brain Cell Genetics Illuminate Alzheimer’s Disease Pathways

Researchers made a significant advance in understanding Alzheimer's disease (AD) by pinpointing how specific brain cells contribute to different stages of the disease. Employing single nucleus RNA sequencing, they analyzed genetic risks in microglia and astrocytes, revealing distinct roles these cells play in AD progression.

Featured Genetics Neurology Neuroscience

·December 4, 2023·4 min read

The Role of Protein Misfolding in Neurodegenerative Diseases

Neurodegenerative diseases share a common factor: protein misfolding and deposits in the brain. Misfolded proteins can lead to toxic activity or the loss of the protein's physiological function, causing damage to neurons.

This shows a man and empty drinking glasses.

Featured Genetics Neuroscience Psychology

·December 1, 2023·4 min read

Peptide PACAP’s Key Role in Alcohol Addiction

Alcohol, the world's most common addictive substance, leads to $249 billion in annual costs and 88,000 deaths in the U.S. Alcohol use disorder affects millions but is under-treated. Researchers discovered a key player in alcohol addiction: pituitary adenylate cyclase activating polypeptide (PACAP).

Featured Genetics Neuroscience Psychology

·November 30, 2023·5 min read

RNA’s Pivotal Role in Fear Memory and PTSD Treatment

Researchers have revealed a groundbreaking role of RNA in fear-related learning and memory. Their study shows how noncoding RNA Gas5 influences neuronal excitability, impacting learning and memory processes.

Featured Genetics Neuroscience

·November 28, 2023·5 min read

Protein Key to Lifespan and Healthy Aging Identified

A new study reveals the significant role of the CD300f immune receptor in determining life expectancy and healthy aging in mice. The absence of this protein in immune system cells, particularly in macrophages and microglia, leads to shorter life spans and pathologies related to cognitive decline and premature aging, with a more pronounced effect in females.

Featured Genetics Neuroscience

·November 28, 2023·5 min read

Unlocking Genes Behind Neurodevelopmental Disorders

Researchers made a significant breakthrough in understanding neurodevelopmental disorders by identifying how three novel genes contribute to these conditions. The study utilized genomic sequencing, phenotyping, and modeling in fly and stem cells to investigate the genetic architecture of these genes. They discovered that malfunctions in the spliceosome, a protein complex responsible for gene splicing, are a key factor in these disorders.

Featured Genetics Neurology Neuroscience

·November 27, 2023·6 min read

Pioneering Stem Cell Therapy for Progressive Multiple Sclerosis Shows Promise

An international team has conducted a groundbreaking study on stem cell therapy for progressive multiple sclerosis (MS). The therapy, involving the injection of neural stem cells into patients' brains, was found to be safe and potentially effective in preventing further brain damage.

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Featured Genetics Neuroscience

·November 21, 2023·4 min read

Genetic Links in Cannabis Use Disorder

Researchers analyzed over 1 million genomes, revealing insights into cannabis use disorder and its ties to psychiatric issues, other substance abuses, and lung cancer risks. The study, part of the Million Veteran Program, identified genetic variants linked to cannabis use disorder and its associated health and behavioral problems.

Featured Genetics Neurology Neuroscience

·November 16, 2023·6 min read

Mutation in Brain’s Immune Cells Linked to Alzheimer’s Risk

A genetic mutation affecting microglia, the brain's immune cells, can increase the risk of Alzheimer's disease up to threefold. The mutation, known as TREM2 R47H/+, impairs microglia function and contributes to Alzheimer's pathology.

Featured Neuroscience

·November 15, 2023·3 min read

Drug-Activated Protein Boosts Memory

Researchers made a breakthrough in memory research by genetically modifying the LIMK1 protein, crucial for memory, to be controlled by the drug rapamycin. This study demonstrates the ability to enhance memory functions by manipulating synaptic plasticity in the brain.

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Genetics

Cellular Atlas of Human Limb Development Created

Key Protein in Frontotemporal Dementia Uncovered

Brain Cell Genetics Illuminate Alzheimer’s Disease Pathways

The Role of Protein Misfolding in Neurodegenerative Diseases

Peptide PACAP’s Key Role in Alcohol Addiction

RNA’s Pivotal Role in Fear Memory and PTSD Treatment

Protein Key to Lifespan and Healthy Aging Identified

Unlocking Genes Behind Neurodevelopmental Disorders

Pioneering Stem Cell Therapy for Progressive Multiple Sclerosis Shows Promise

Genetic Links in Cannabis Use Disorder

Mutation in Brain’s Immune Cells Linked to Alzheimer’s Risk

Drug-Activated Protein Boosts Memory

Light Therapy Shines in Treating Alzheimer’s Sleep and Mood Issues

Cellular Atlas of Human Limb Development Created

Key Protein in Frontotemporal Dementia Uncovered

Brain Stimulation Enhances Alzheimer’s Cognitive Function

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