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Genetics

Featured Neuroscience Visual Neuroscience

·May 8, 2023·5 min read

High-Resolution Image of the Human Retina Reveals Stunning Details

Researchers developed a new imaging technique to visualize several dozen proteins in a thin tissue section at high resolution using fluorescence microscopy.

Featured Genetics Neuroscience

·May 8, 2023·5 min read

Neanderthal DNA Shapes Human Nose

A specific gene inherited from Neanderthals may be responsible for the shape of our noses. The researchers found the gene contributes to nasal height and may have been inherited from the ancient human ancestor to help humans adapt to colder climates as our ancestors moved out of Africa.

Featured Genetics Neuroscience

·May 6, 2023·4 min read

Breaking the Darkness: Reactivating Dormant Cells in the Retina Brings New Hope for Vision Regeneration

Researchers discovered a way to reactivate dormant cells in the retina of mice to restore vision, without the need for transplantation. The team discovered dormant glial cells can be transformed into cells sharing properties with cone photoreceptors, which enable color perception, reading and driving. The approach, which uses two genes to transform Müller cells into retinal neurons, could offer new hope for developing regenerative therapies to replace lost cells in retinal degeneration.

Featured Neuroscience Pain

·May 4, 2023·6 min read

Underlying Mechanism of Neuropathic Pain Revealed

The enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord is responsible for initiating and maintaining neuropathic pain. Targeting spinal Tiam1 with anti-sense oligonucleotides injected into the cerebrospinal fluid effectively alleviates pain hypersensitivity.

Featured Genetics Neuroscience

·April 30, 2023·6 min read

Uncovering the Human Genome’s Secrets: 240 Mammalian Species Shed Light on What Makes Us Unique

Researchers analyzed the DNA sequences from 240 mammalian species, showing how comparative genomics can shed light on how certain species achieve extraordinary feats and help scientists better understand the functional parts of the human genome. By identifying regions of the genomes that are most conserved across mammalian species, they pinpointed the genetic basis for uncommon mammalian traits, such as the ability to hibernate or detect faint scents from miles away. They also found genetic variants that are more likely to play causal roles in rare and common human diseases.

Featured Neurology Neuroscience

·April 27, 2023·6 min read

Researchers Discover Protein That May Help Resist Dementia Despite Plaque Buildup

Researchers have discovered a protein, neuritin, that is associated with cognitive resilience to Alzheimer’s disease and may delay cognitive decline. This protein helps retain neuronal connections, even when toxic substances such as amyloid beta plaques and tau tangles that cause Alzheimer's try to break them down.

Featured Genetics Neuroscience Psychology

·April 27, 2023·5 min read

Identification of DNA Methylation Markers in Newborns for Increased Schizophrenia Risk

Researchers identified DNA methylation markers that may indicate the risk of developing schizophrenia later in life in newborns. This breakthrough discovery could allow for early detection and intervention to reduce the impact of the disease. By studying blood samples collected at birth, the team was able to identify unique methylation differences in cell types that could become potential clinical biomarkers for future early detection of schizophrenia.

Featured Genetics Neuroscience Visual Neuroscience

·April 26, 2023·3 min read

Gene Therapy for Dogs With Inherited Blinding Eye Disease Set for Human Trials

A groundbreaking gene therapy proven successful in treating an inherited, blinding eye disease in dogs is now poised for clinical trials in humans with the rare condition retinitis pigmentosa. The therapy, which halts vision loss by introducing a normal copy of the CNGB1 gene, could potentially benefit around 2 million people affected worldwide.

Featured Genetics Neuroscience

·April 25, 2023·4 min read

Unraveling the Genetic Mechanisms Behind Long-Lasting Memories in the Brain

Researchers shed new light on the molecular and genetic basis of long-term memory formation in the brain. A new study reveals a single stimulation to the synapses of hippocampal neurons triggered numerous cycles where the memory-coding Arc gene produced mRNA molecules that were then translated into synapse-strengthening Arc proteins. From the findings, researchers determined a novel feedback loop that helps explain how short-lived mRNA and proteins create long-term memories in the brain.

Featured Genetics Neuroscience Psychology

·April 25, 2023·4 min read

Genetic Driver of Anxiety Discovered

An international team of scientists has identified a gene in the brain responsible for anxiety symptoms and found that modifying the gene can reduce anxiety levels, offering a novel drug target for anxiety disorders. The discovery highlights a new amygdala miR483-5p/Pgap2 pathway that regulates the brain's response to stress and provides a potential therapeutic approach for anxiety disorders.

Featured Neurology Neuroscience

·April 24, 2023·4 min read

Antiviral Pathway a Potential New Target for Alzheimer’s Treatment

Inhibiting cGAS, an innate immune system enzyme allows neurons to become more resilient to tau fibrils. The new finding may serve in the development of new therapies to help treat Alzheimer's disease and frontotemporal dementia, two neurodegenerative disorders associated with tau build-up in the brain.

This shows a genetically engineered worm

Featured Neuroscience

·April 23, 2023·6 min read

Worm Model Weeds Out New Insight Into Endocannabinoid System

A new study of worms brings new insight into the workings of the endocannabinoid system and helps answer the question of why cannabis consumption enhances mood and gives people "the munchies". Researchers found cannabis consumption activates the endocannabinoid system and evokes cravings for higher calorie foods.

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Genetics

High-Resolution Image of the Human Retina Reveals Stunning Details

Neanderthal DNA Shapes Human Nose

Breaking the Darkness: Reactivating Dormant Cells in the Retina Brings New Hope for Vision Regeneration

Underlying Mechanism of Neuropathic Pain Revealed

Uncovering the Human Genome’s Secrets: 240 Mammalian Species Shed Light on What Makes Us Unique

Researchers Discover Protein That May Help Resist Dementia Despite Plaque Buildup

Identification of DNA Methylation Markers in Newborns for Increased Schizophrenia Risk

Gene Therapy for Dogs With Inherited Blinding Eye Disease Set for Human Trials

Unraveling the Genetic Mechanisms Behind Long-Lasting Memories in the Brain

Genetic Driver of Anxiety Discovered

Antiviral Pathway a Potential New Target for Alzheimer’s Treatment

Worm Model Weeds Out New Insight Into Endocannabinoid System

Jiving into Joy: Dance Sessions Elevate Health and Well-being in 85+ Age Group

New Insights Into Synaptic Pruning During Brain Development

Childhood IQ and Wealth: Uncovering Diverse Financial Paths in Adulthood

Stressed Brains Amplify Comfort Food Cravings

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