Infiltrating gliomas are shaped by their genetic evolution and microenvironment, researchers report. The findings may help in the development of therapies to treat glioma brain tumors.
Researchers identified LIPE, a lipase that degrades triglycerides to produce fatty acids, as a potential new target for the development of treatments for Parkinson's disease.
People who suffer cardiometabolic disorders, such as stroke, diabetes, or a heart attack, either as stand-alone conditions or a combination of the conditions, have an increased risk of developing dementia regardless of whether or not they have a genetic predisposition for neurodegeneration.
Researchers have identified a new genetic eye disease that affects the macula.
People with higher levels of omega-3 DHA in their blood are 49% less likely to develop dementia than those with lower levels. Researchers say adding additional omega-3 DHA to the diet, especially in those with the Alzheimer's associated Apoe4 gene, could slow the development and progress of dementia.
The Parkinson's-associated protein alpha-synuclein appears to act as a "toggle switch" that helps control vesicle transportation and gene expression. In a diseased state, this delicate balance is broken. The findings have implications for the development of new treatments for Parkinson's disease.
An immune protein called CSF1 may contribute to feelings of anxiety as a result of alcohol withdrawal for those with alcohol use disorder.
The aged non-human primate hippocampus showed signs of increased inflammation, genomic and epigenomic instability, and a loss of proteostasis.
Rapamycin, a drug approved for the treatment of cancer and transplant patients increases amyloid-beta protein plaques in the brains of mice.
A new injectable therapy that uses specially engineered molecules could help treat spinal cord injury.
Researchers have identified the cellular and molecular mechanisms that regulate selective autophagy.
A new study sheds light on how the neocortex in the human brain develops.
