A brain-penetrating experimental drug in development as a cancer treatment can foster the regeneration of damaged nerves following spinal cord injury, researchers report.
Researchers have developed a new experimental human cell line from retinal pigment epithelial cells, dubbed ABC cells, that can assist with the study of blinding eye diseases, including age-related macular degeneration.
Researchers say pharmacogenomics can assist providers in determining the best antidepressant treatments for patients with depression and avoid prescribing medications that could have adverse effects.
Targeting the GAT3 protein in the thalamus could help block and prevent long-term damage following brain injury.
Alpha-synuclein proteins form into unusual shapes when exposed to large quantities of copper ions. Researchers say the effect of environmental copper exposure on alpha-synuclein could play a role in the pathogenesis of Parkinson's disease.
Paternal depression may contribute to adolescent depression and behavioral problems, regardless of whether or not the father and child are genetically related, researchers say.
Researchers identified differences in isoforms that control Treg cells and how that affects the body's immune system response.
Mutations in the ASD/intellectual disability genes ADNP and POGZ result in abnormal activation and overexpression of immune response genes and genes for microglia. This results in abnormal brain synaptic function, characteristic of ASD and ID.
Oxidative damage to telomeres can trigger cellular senescence. The findings could lead to the development of new therapeutics for healthy aging and to combat cancers.
Researchers reveal the critical role the p62 gene plays in the selective autophagy of tau oligomers.