neuropsychopharmacology

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Psychedelic drugs: would you accept a prescription? It depends if you’ve tried them before

Numerous studies have linked controlled psychedelics to improvements in mental health conditions such as depression and PTSD. In March, the FDA approved Esketamine as a treatment for depression. However, with much stigma surrounding psychedelics, researchers question how many patients would take psychedelic medications if prescribed to them. According to a new study, 40% of people with no experience of psychedelics would be unlikely to take the prescription due to fears of 'brain damage' or a 'bad trip'.... Read More...
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Common antidepressants interact with opioid med to lessen pain relief

SSRI antidepressants, such as Prozac and Paxil, interact with opioid medications to make them less effective at providing relief from chronic pain. Tramadol relies on activation of the CYP2D6 enzyme to control pain, but SSRIs inhibit this enzyme. Researchers suggest prescribing different classes of antidepressants which do not suppress the enzyme may benefit those in need of opioid medications. Alternatively, non-opioid pain killers should be considered for those who can not switch from SSRIs.... Read More...
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‘Ecstasy’ shows promise for post-traumatic stress treatment

MDMA shows promise for the treatment of post-traumatic stress disorder. Combining the use of Ecstasy with psychotherapy treatments resulted in a reduction of PTSD symptoms after just one session. 54% of the study participants no longer met the PTSD criteria after two sessions. Patients also reported improvements in depression symptoms.... Read More...
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Ketamine: The illicit party psychedelic that promises to heal depression

Ketamine, an anesthetics which has been commonly used as an illicit party drug, is helping people overcome depression. The drug works rapidly and provides lasting relief from depressive symptoms for weeks after exposure. Researchers are examining how ketamine works in the brain to help positively influence behavior in those with mood disorders.... Read More...