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neuropsychopharmacology

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·April 14, 2022·5 min read

A Drug That Cures Alcoholism May Be the Next Anti-anxiety Medication

Disulfiram, a drug commonly prescribed to treat chronic alcohol addiction, was shown to reduce anxiety levels in rodent models. The drug inhibits FROUNT protein and chemokine signaling pathways under its influence, suppressing overall glutamate transmission in the brain. This, in turn, helps reduce overall activity. The findings may signal a new way to treat anxiety in humans.

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·March 18, 2022·4 min read

Researchers Explore Therapeutic Uses of Ketamine

Researchers report ketamine may have a broader use for the treatment of psychological disorders beyond a treatment for depression and anxiety.

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·March 16, 2022·3 min read

Largest Ever Psychedelics Study Maps Changes of Conscious Awareness to Neurotransmitter Systems

Study reveals how psychedelic drug-induced changes in subjective awareness are rooted in specific neurotransmitter systems.

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·March 6, 2022·2 min read

How Long-Term Benzodiazepine Use Leads to Cognitive Impairments

Mouse study reveals synaptic loss associated with a daily sleep-inducing dose of diazepam for several weeks leads to cognitive impairments. However, the effect was reversible after discontinuing benzodiazepine use.

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·November 19, 2021·5 min read

Psychedelics Show Promise in Treating Mental Illness

A growing body of evidence suggests psychedelics including psilocybin and LSD show promise in providing lasting relief from symptoms for those suffering some mental health disorders. Researchers found DOI, a similar drug to LSD, reduced negative behavioral responses following fear triggers in mouse models of anxiety.

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·October 22, 2021·4 min read

Common Antidepressant Should No Longer Be Used to Treat People With Dementia

Mirtazapine, an antidepressant commonly prescribed to treat dementia-associated agitation, is no more effective than a placebo and may increase mortality risks, researchers report.

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·October 14, 2021·4 min read

Brain Activity Fluctuations May Hold the Keys to Psychiatric Treatment Efficacy

Moment-to-moment fluctuations in brain activity over a three-minute period can reliably predict how receptive a person with social anxiety will be to cognitive behavioral therapy.

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·July 25, 2021·4 min read

The Future of Psychedelic Science

From treating depression and other mental health disorders, to helping relieve chronic pain, researchers discuss the advantages and implications of psychedelic treatments.

Featured Neuroscience Psychology

·July 7, 2021·4 min read

Work Like a Dream: New Anticholinergic Drug Keeps PTSD Flashbacks and Nightmares Away

Trihexyphenidyl, an anticholinergic medication commonly prescribed for Parkinson's symptoms, appears to alleviate negative memory flashbacks and nightmares experienced by those with PTSD.

Featured Neuroscience Open Neuroscience Articles Psychology

·May 3, 2021·4 min read

Same Drug Can Have Opposite Effects on Memory Depending on Sex

Osanetant, a drug that inhibits the Tac2 pathway, has opposite effects on the recall of traumatic events in male and female mice.

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Featured Neuroscience Psychology

·April 6, 2021·4 min read

Resurging Psychedelic Therapies for Depression

As interest in using psychedelics to treat a range of mental health disorders grows, researchers consider the impact and therapeutic benefits of using psychedelics to help alleviate symptoms of depression.