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myelin

Featured Genetics Neurology Neuroscience

·October 4, 2019·4 min read

Targeting certain rogue T cells prevents and reverses multiple sclerosis: Mouse study

TH17 cells produced increased amounts of SerpinB1, a protein implicated in multiple sclerosis symptoms. SerpinB1 cells were identified with antibodies targeting the CXCR6 surface protein. Using monoclonal antibodies to target CXCR6, the cells disappeared significantly, and the mice primed to develop MS did not develop the disease.

This is a brain slice scan from the study

Featured Neuroscience Open Neuroscience Articles

·September 24, 2019·4 min read

Do children’s brains really get thinner?

A new study questions whether a child's brain thins as they get older. Researchers say the cortex does not thin during childhood, but instead becomes more myelinated.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·August 21, 2019·4 min read

‘Key player’ identified in genetic link to psychiatric conditions

CYFIP1 plays a key role in the damaging effects of 15q11.2 deletion. When CYFIP1 is missing, myelin abnormalities occur. The findings shed light on how psychiatric disorders, such as schizophrenia and autism, may develop.

Featured Neurology Neuroscience Pain

·August 15, 2019·2 min read

New pain organ discovered in the skin

In a groundbreaking finding, researchers have identified a new sensory organ under the skin that can detect pain as a result of impact or pinpricks. The organ comprises of glial cells with multiple long protrusions which collectively make up the mesh-like organ under the skin.

Featured Genetics Neuroscience

·August 14, 2019·3 min read

Scientists reverse aging process in rat brain stem cells

Removing Piezo1 from the surface of aged brain stem cells caused the cells to become rejuvenated and regain their normal regenerative function.

Featured Neuroscience Open Neuroscience Articles Psychology

·August 13, 2019·4 min read

Glial cells are critical players in brain’s response to social stress

The behavior of oligodendrocytes plays a critical role in determining whether we tolerate or succumb to stress.

Featured Genetics Neurology Neuroscience

·July 15, 2019·5 min read

Differences in MS patients’ cerebrospinal fluid may be key to drugs that halt progression

Ceramide exposure impairs the ability for neurons to make energy by directly damaging mitochondria. Additionally, ceramides force neurons to rapidly uptake glucose in order to provide cellular energy.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·July 5, 2019·4 min read

Discovery reveals prolific ability of Schwann cells to generate myelin

Schwann cells are much more prolific in generating myelin than previously believed. Knocking out the fbxw7 gene in mouse models, researchers discovered individual Schwann cells began to spread myelin across many axons.

Neuroscience

·July 3, 2019·4 min read

Pain signaling in humans more rapid than previously known

Pain signaling occurs much faster than previously believed. Researchers report thickly myelinated nerves contribute to pain processing speeds.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles Psychology

·May 14, 2019·4 min read

How stressed-out gut bacteria may trigger autoimmune response

Chronic social stress in mice induces the expression of virulent genes in the gut microbiota. The altered microbiota increases the presence of effector T helper cells in the lymph nodes and induces myelin autoreactive cells. Exposure to chronic stress, therefore, may increase the risk of developing autoimmune diseases for some individuals with a susceptibility.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·May 6, 2019·5 min read

Pigment-producing stem cells can regenerate myelin sheath: Mouse study

Skin-related stem cells may be key to helping restore the myelin sheath in patients with multiple sclerosis. Using mouse models, researchers discovered melanocyte stem cells can, under the right conditions, function as cells that create myelin.

oligodendrocytes from alzheimer's brain tissue are shown

Featured Genetics Neurology Neuroscience

·May 1, 2019·6 min read

A comprehensive map of how Alzheimer’s affects the brain

Axon myelination is significantly disrupted in patients with Alzheimer's disease. Researchers also found brain cells of men and women vary significantly in how their genes respond to the neurodegenerative disease.