CYFIP1 plays a key role in the damaging effects of 15q11.2 deletion. When CYFIP1 is missing, myelin abnormalities occur. The findings shed light on how psychiatric disorders, such as schizophrenia and autism, may develop.
Researchers report they have successfully developed 'mini-brains' made up of the many neurons and cells in the human brain. The mini brains could allow for better research and reduce the need for animal testing.
Axon myelination is significantly disrupted in patients with Alzheimer's disease. Researchers also found brain cells of men and women vary significantly in how their genes respond to the neurodegenerative disease.
Renewed, thin myelin sheaths are sufficient to help restore nervous system impairments in diseases like multiple sclerosis, a new study in PNAS reports.
A small-molecule metabolite produced by gut bacteria in mice, can travel to the brain and alter brain cell function, inducing anxiety behaviors.
A global knockout of the thrombin receptor PAR1 accelerates myelin development. The findings could help with the development of treatments for diseases associated with demyelination, like multiple sclerosis.
A new study identifies a possible genetic mechanism that causes a quicker progression of multiple sclerosis. The absence of Tob1 in CD4+ T cells is key to early onset of a more aggressive form of MS.
UCSF researchers reveal a common over the counter antihistamine appears to accelerate neural signaling and restore nervous system functioning for some multiple sclerosis patients.
An experimental treatment can generate immune cells that migrate to the brain and prevent attacks against myelin, allowing mice the ability to regain walking skills.