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myelin

·November 6, 2020·4 min read

New Strategies for Restoring Myelin on Damaged Nerve Cells

Researchers have discovered a two-pronged approach to restore myelin on regenerated axons in a mouse model of optic nerve damage. The findings have positive implications for the treatment of multiple sclerosis.

This shows a brain slice with a border between white and gray matter

Featured Neuroscience Open Neuroscience Articles

·October 19, 2020·3 min read

What Lies Between Grey and White in the Brain

Researchers have succeeded in making superficial white matter visible in a living human brain.

Featured Neurology

·October 7, 2020·3 min read

Simple Sugar Possible Therapy for Repairing Myelin in Multiple Sclerosis

N-acetylglucosamine, a simple sugar found in breast milk, promotes remyelination in mouse models of multiple sclerosis. The findings could have implications for treating multiple sclerosis in humans.

Featured Genetics Neurology Open Neuroscience Articles

·August 24, 2020·5 min read

Mechanisms Identified to Restore Myelin Sheaths After Injury or in Multiple Sclerosis

eEF1a1 activated by acetylation prevents remyelination, but if the protein is deactivated by deacetylation, myelin sheaths can be rebuilt. The findings shed light on the process of remyelination and could provide avenues of treatment for multiple sclerosis, and other conditions associated with demyelination.

Featured Neurology

·August 17, 2020·3 min read

Cashew Shell Compound Appears to Mend Damaged Nerves

Anacardic acid, a compound found in cashew shells, promotes the repair of myelin. The findings could have positive implications for the treatment of diseases, such as multiple sclerosis, that are characterized by demyelination.

Featured Genetics Neurology Neuroscience

·May 19, 2020·2 min read

Animal study shows human brain cells repair damage in multiple sclerosis

Human iPSCs transplanted into animal models of multiple sclerosis help repair cell damage and restore function.

Featured Neurology Neuroscience

·May 14, 2020·4 min read

Local inflammatory cells are characteristic for advanced multiple sclerosis

In late-stage multiple sclerosis, inflammatory cells no longer enter the brain via the bloodstream, but instead the cells arise in memory from local memory cells inside the brain. The findings suggest during the late phases of multiple sclerosis, the disease is occurring entirely inside the brain.

Featured Neuroscience Open Neuroscience Articles Psychology

·April 29, 2020·4 min read

Schizophrenia related to abnormal fatty metabolism in the brain

People with schizophrenia have lower levels of S1P, a type of fatty molecule found in white matter. Evaluating post mortem tissue of those who died from a range of psychiatric disorders, researchers found the decreased levels of S1P in the brain was only attributed to those with schizophrenia. The findings could lead to new targeted treatments for the mental health disorder.

Featured Neurology Neuroscience

·April 6, 2020·4 min read

Compound in fruit peels halts damage and spurs neuronal repair in multiple sclerosis

Ursolic acid, a compound abundant in fruit peels and some herbs, appears to decrease further neural damage and help regenerate myelin in mouse models of multiple sclerosis. Study reveals ursolic acid suppresses TH17 cells, which are one of the main drivers in the pathological autoimmune response of MS.

Featured Neurology Neuroscience

·March 28, 2020·3 min read

FDA approves ozanimod for treatment of multiple sclerosis

The FDA has approved a new drug named Ozanimod for the treatment of multiple sclerosis. Ozanimod binds to receptors in lymphocytes' surfaces, preventing them from reaching the brain. As the number of active lymphocytes decreases, the attack on the immune system diminishes.