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myelin

·August 14, 2019·3 min read

Scientists reverse aging process in rat brain stem cells

Removing Piezo1 from the surface of aged brain stem cells caused the cells to become rejuvenated and regain their normal regenerative function.

Featured Neuroscience Open Neuroscience Articles Psychology

·August 13, 2019·4 min read

Glial cells are critical players in brain’s response to social stress

The behavior of oligodendrocytes plays a critical role in determining whether we tolerate or succumb to stress.

Featured Genetics Neurology Neuroscience

·July 15, 2019·5 min read

Differences in MS patients’ cerebrospinal fluid may be key to drugs that halt progression

Ceramide exposure impairs the ability for neurons to make energy by directly damaging mitochondria. Additionally, ceramides force neurons to rapidly uptake glucose in order to provide cellular energy.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·July 5, 2019·4 min read

Discovery reveals prolific ability of Schwann cells to generate myelin

Schwann cells are much more prolific in generating myelin than previously believed. Knocking out the fbxw7 gene in mouse models, researchers discovered individual Schwann cells began to spread myelin across many axons.

Neuroscience

·July 3, 2019·4 min read

Pain signaling in humans more rapid than previously known

Pain signaling occurs much faster than previously believed. Researchers report thickly myelinated nerves contribute to pain processing speeds.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles Psychology

·May 14, 2019·4 min read

How stressed-out gut bacteria may trigger autoimmune response

Chronic social stress in mice induces the expression of virulent genes in the gut microbiota. The altered microbiota increases the presence of effector T helper cells in the lymph nodes and induces myelin autoreactive cells. Exposure to chronic stress, therefore, may increase the risk of developing autoimmune diseases for some individuals with a susceptibility.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·May 6, 2019·5 min read

Pigment-producing stem cells can regenerate myelin sheath: Mouse study

Skin-related stem cells may be key to helping restore the myelin sheath in patients with multiple sclerosis. Using mouse models, researchers discovered melanocyte stem cells can, under the right conditions, function as cells that create myelin.

oligodendrocytes from alzheimer's brain tissue are shown

Featured Genetics Neurology Neuroscience

·May 1, 2019·6 min read

A comprehensive map of how Alzheimer’s affects the brain

Axon myelination is significantly disrupted in patients with Alzheimer's disease. Researchers also found brain cells of men and women vary significantly in how their genes respond to the neurodegenerative disease.

This shows the myelin regrowth on neurons

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 25, 2019·3 min read

Stem cells from hair follicles have potential to repair myelin sheath in mice

Melanocyte stem cells from human hair follicles that carry CD34 have the ability to turn into glial cells. The CD34+ stem cells can regenerate myelin, both on neurons and in mouse models with a genetic defect that prevents the formation of healthy myelin sheaths. The findings could have positive implications for the treatment of demyelinating diseases, such as Multiple Sclerosis.

Featured Genetics Neuroscience Psychology

·April 24, 2019·4 min read

Hypersociability in Williams syndrome result of Myelination deficits

Myelin thickness and oligodendrocytes were significantly reduced in the prefrontal cortex in mouse models of Williams syndrome.

Featured Neurology Neuroscience Open Neuroscience Articles

·April 18, 2019·5 min read

Study shows promise in repairing damaged myelin

A study in mouse models of multiple sclerosis demonstrates a compound called sobetirome promotes remyelination, and a derivative of the compound can penetrate the blood-brain barrier to enable a tenfold increase in infiltration to the CNS. Researchers are confident their research will translate from mice into humans, providing a new avenue of treatment for MS.

Brain images are shown with some areas highlighted.

Electrophysiology Featured Neuroscience

·March 28, 2019·3 min read

New pattern of brain ageing identified

New patterns of brain ageing across the human lifespan have been revealed by researchers analysing microstructural changes in the brain’s white matter.