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·May 14, 2019·4 min read

How stressed-out gut bacteria may trigger autoimmune response

Chronic social stress in mice induces the expression of virulent genes in the gut microbiota. The altered microbiota increases the presence of effector T helper cells in the lymph nodes and induces myelin autoreactive cells. Exposure to chronic stress, therefore, may increase the risk of developing autoimmune diseases for some individuals with a susceptibility.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·May 6, 2019·5 min read

Pigment-producing stem cells can regenerate myelin sheath: Mouse study

Skin-related stem cells may be key to helping restore the myelin sheath in patients with multiple sclerosis. Using mouse models, researchers discovered melanocyte stem cells can, under the right conditions, function as cells that create myelin.

oligodendrocytes from alzheimer's brain tissue are shown

Featured Genetics Neurology Neuroscience

·May 1, 2019·6 min read

A comprehensive map of how Alzheimer’s affects the brain

Axon myelination is significantly disrupted in patients with Alzheimer's disease. Researchers also found brain cells of men and women vary significantly in how their genes respond to the neurodegenerative disease.

This shows the myelin regrowth on neurons

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 25, 2019·3 min read

Stem cells from hair follicles have potential to repair myelin sheath in mice

Melanocyte stem cells from human hair follicles that carry CD34 have the ability to turn into glial cells. The CD34+ stem cells can regenerate myelin, both on neurons and in mouse models with a genetic defect that prevents the formation of healthy myelin sheaths. The findings could have positive implications for the treatment of demyelinating diseases, such as Multiple Sclerosis.

Featured Genetics Neuroscience Psychology

·April 24, 2019·4 min read

Hypersociability in Williams syndrome result of Myelination deficits

Myelin thickness and oligodendrocytes were significantly reduced in the prefrontal cortex in mouse models of Williams syndrome.

Featured Neurology Neuroscience Open Neuroscience Articles

·April 18, 2019·5 min read

Study shows promise in repairing damaged myelin

A study in mouse models of multiple sclerosis demonstrates a compound called sobetirome promotes remyelination, and a derivative of the compound can penetrate the blood-brain barrier to enable a tenfold increase in infiltration to the CNS. Researchers are confident their research will translate from mice into humans, providing a new avenue of treatment for MS.

Brain images are shown with some areas highlighted.

Electrophysiology Featured Neuroscience

·March 28, 2019·3 min read

New pattern of brain ageing identified

New patterns of brain ageing across the human lifespan have been revealed by researchers analysing microstructural changes in the brain’s white matter.

Featured Genetics Neurology Neuroscience

·January 29, 2019·5 min read

Researchers Generate and Track Development of Myelin Producing Brain Cells

Researchers have successfully created stem cell derived brain cells which can generate oligodendrocytes, neurons and astrocytes.

Featured Genetics Neurology Neuroscience

·January 23, 2019·5 min read

Shedding Light on Brain Cell Changes in Multiple Sclerosis

A new study sheds light on brain cells implicated in multiple sclerosis. Researchers found there are several types of oligodendrocytes, and the ratio of these cells differ significantly in those with MS. The findings could help develop new targeted treatments for progressive multiple sclerosis.

Featured Neurology

·January 22, 2019·4 min read

Shedding Light on Spinal Cord Injuries

Study reveals the immune system response may contribute to additional injury following damage to the spinal cord.

Featured Neurology Open Neuroscience Articles

·January 22, 2019·4 min read

Helping Cells to Help Themselves May Benefit Multiple Sclerosis

Researchers have discovered how the body is able to initiate repair mechanisms which can limit the extent of damage to the myelin sheath. The findings could help with the development of new therapies for multiple sclerosis.