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amyloid-beta

·July 15, 2020·4 min read

Super-Agers Show Resistance to Tau and Amyloid Accumulation

PET neuroimaging reveals super-agers and those whose cognitive skills are above the norm for an advanced age have an increased resistance to tau and amyloid proteins.

Featured Genetics Neurology

·June 23, 2020·5 min read

New gene may drive earliest brain changes in Alzheimer’s

Genetic analysis of almost 4,300 samples reveals a link between the appearance of amyloid deposits, APOE, and a novel gene called RBFOX1. Lower levels of RBFOX1 in the brain appear to be associated with increased amyloid and global cognitive decline over a person's lifetime.

Featured Neurology Neuroscience Open Neuroscience Articles

·May 29, 2020·2 min read

How toxic protein spreads in Alzheimer’s disease

Tau spreads through the human brain via neural communication pathways. The spread is accelerated by the presence of amyloid-beta.

Featured Neurology Neuroscience

·May 11, 2020·4 min read

3D brain-like tissue model links Alzheimer’s disease with herpes

A 3D human tissue culture model demonstrated a possible causal relationship between Alzheimer's disease and herpes simplex virus 1 (HSV-1) infection. 40 Alzheimer's associated genes were over-expressed in the HSV-1 infected brain tissue, including genes associated with the production of amyloid-beta.

Featured Neurology Neuroscience Open Neuroscience Articles

·April 30, 2020·6 min read

Nanodevices for the brain could thwart formation of Alzheimer’s plaques

Researchers have developed a new approach to prevent amyloid plaque formation by engineering a nanodevice that captures the peptides before they can assemble. The silica nanodevice might be a new tool in the treatment and prevention of Alzheimer's disease and other neurodegenerative diseases associated with amyloid-beta.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·March 18, 2020·5 min read

Alzheimer’s risk genes converge on microglia

Findings indicate a large part of the genetic risk of Alzheimer's involves a microglial response to amyloid-beta.

Featured Neurology Neuroscience

·February 17, 2020·4 min read

Beta-arrestin-2 increases neurotoxic tau driving frontotemporal dementia

The protein beta-arrestin-2 increases tau tangle accumulation in Alzheimer's disease and frontotemporal dementia but interfering with the removal of excess tau from the brain.

Featured Genetics Neurology Neuroscience

·February 14, 2020·4 min read

Subtle decline in cognition predicts progression to Alzheimer’s pathology

Cognitive performance may predict the progression from normal to abnormal levels of Alzheimer's associated amyloid-beta.

$This is a diagram from the study$

Featured Neuroscience Open Neuroscience Articles

·January 28, 2020·3 min read

New mathematical model for amyloid formation

Mathematical model describes the chemical reactions responsible for the formation of Alzheimer's-linked protein.

This shows an old man sitting on a park bench

Featured Neurology Neuroscience

·January 25, 2020·5 min read

Lithium may halt Alzheimer’s progression

More commonly associated with treating bipolar disorder, microdoses of lithium may halt the progression of Alzheimer's disease.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 21, 2020·4 min read

Possible Alzheimer’s breakthrough suggested

A previously unknown gene and associated protein have been linked to the development of Alzheimer's disease. By suppressing the protein, named Aggergatin by the researchers, it may be possible to slow down or prevent the development of the neurodegenerative disease.

This shows amyloid beta and aluminum traces in the brain sample

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 20, 2020·3 min read

Human Exposure to Aluminum Linked to Familial Alzheimer’s Disease

Researchers found a close association between high aluminum content in brain tissue and amyloid-beta location in post-mortem samples of people with familial Alzheimer's disease. The findings back up previous claims that aluminum exposure may be linked to the development of the neurodegenerative disease.

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amyloid-beta

Super-Agers Show Resistance to Tau and Amyloid Accumulation

New gene may drive earliest brain changes in Alzheimer’s

How toxic protein spreads in Alzheimer’s disease

3D brain-like tissue model links Alzheimer’s disease with herpes

Nanodevices for the brain could thwart formation of Alzheimer’s plaques

Alzheimer’s risk genes converge on microglia

Beta-arrestin-2 increases neurotoxic tau driving frontotemporal dementia

Subtle decline in cognition predicts progression to Alzheimer’s pathology

New mathematical model for amyloid formation

Lithium may halt Alzheimer’s progression

Possible Alzheimer’s breakthrough suggested

Human Exposure to Aluminum Linked to Familial Alzheimer’s Disease

New Math Method Inflates Alzheimer’s Drug Success by 29x

Genetic Maps Target Root Causes of Multiple Sclerosis

Cooperation Emerges Naturally Through Recognition

Brain Rewires to Stabilize Walking During Visual Impairment

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