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amyloid-beta

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Featured Neurology Neuroscience Open Neuroscience Articles

·August 18, 2020·3 min read

Links Found Between Diabetes Blood Markers and Alzheimer’s Pathology

Study reveals a link between amyloid-beta accumulation in the brain and lower levels of insulin and insulin resistance.

Featured Neurology Open Neuroscience Articles

·August 11, 2020·3 min read

Right Under Your Nose: A More Convenient Way to Diagnose Alzheimer’s

Analyzing nasal discharge could be a new tool in diagnosing and monitoring the progression of Alzheimer's disease. Researchers found certain Alzheimer's related proteins can be detected in nasal discharge.

Featured Neurology

·July 27, 2020·3 min read

Temporary Salt Crystals May Provide a Permanent Solution to Alzheimer’s

Salt crystals can precipitate at low concentrations due to local density fluctuations. Their repeated precipitation dissolution behavior promotes amyloid-beta peptide aggregation.

Featured Neurology

·July 20, 2020·4 min read

Oxytocin Could Be Used to Treat Cognitive Disorders Like Alzheimer’s

Oxytocin, the so-called "love hormone," could help to treat cognitive disorders, including Alzheimer's disease. Researchers demonstrated oxytocin reversed the effects of amyloid-beta on hippocampal LTP in mice. The findings suggest oxytocin could be used as a therapeutic for the treatment of Alzheimer's disease and other dementias.

Featured Neurology

·July 15, 2020·4 min read

Super-Agers Show Resistance to Tau and Amyloid Accumulation

PET neuroimaging reveals super-agers and those whose cognitive skills are above the norm for an advanced age have an increased resistance to tau and amyloid proteins.

Featured Genetics Neurology

·June 23, 2020·5 min read

New gene may drive earliest brain changes in Alzheimer’s

Genetic analysis of almost 4,300 samples reveals a link between the appearance of amyloid deposits, APOE, and a novel gene called RBFOX1. Lower levels of RBFOX1 in the brain appear to be associated with increased amyloid and global cognitive decline over a person's lifetime.

Featured Neurology Neuroscience Open Neuroscience Articles

·May 29, 2020·2 min read

How toxic protein spreads in Alzheimer’s disease

Tau spreads through the human brain via neural communication pathways. The spread is accelerated by the presence of amyloid-beta.

Featured Neurology Neuroscience

·May 11, 2020·4 min read

3D brain-like tissue model links Alzheimer’s disease with herpes

A 3D human tissue culture model demonstrated a possible causal relationship between Alzheimer's disease and herpes simplex virus 1 (HSV-1) infection. 40 Alzheimer's associated genes were over-expressed in the HSV-1 infected brain tissue, including genes associated with the production of amyloid-beta.

Featured Neurology Neuroscience Open Neuroscience Articles

·April 30, 2020·6 min read

Nanodevices for the brain could thwart formation of Alzheimer’s plaques

Researchers have developed a new approach to prevent amyloid plaque formation by engineering a nanodevice that captures the peptides before they can assemble. The silica nanodevice might be a new tool in the treatment and prevention of Alzheimer's disease and other neurodegenerative diseases associated with amyloid-beta.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·March 18, 2020·5 min read

Alzheimer’s risk genes converge on microglia

Findings indicate a large part of the genetic risk of Alzheimer's involves a microglial response to amyloid-beta.

Featured Neurology Neuroscience

·February 17, 2020·4 min read

Beta-arrestin-2 increases neurotoxic tau driving frontotemporal dementia

The protein beta-arrestin-2 increases tau tangle accumulation in Alzheimer's disease and frontotemporal dementia but interfering with the removal of excess tau from the brain.