A metallic molecule allows for real time motoring of amyloid beta plaques.
Researchers use a newly developed imaging technique that makes tissue transparent to visualize brain tissue from deceased patients with Alzheimer's disease.
A new mouse study reveals a breakdown in the process that clears brain cells of waste products precedes the buildup of amyloid plaques associated with Alzheimer's disease.
Researchers discover a way to traverse the blood-brain barrier and retinal-blood barrier to deliver a molecule which degrades the main component of Alzheimer's plaques.
According to a new study, protein PITRM1 may be involved in the development of Alzheimer's disease.
A combination of patient-reported subjective cognitive impairment and measurable clinical symptoms, such as amyloid-beta accumulation in the cerebrospinal fluid, may help in the early diagnosis of Alzheimer's disease.
Researchers report a drug called fasudil may help to prevent synapse loss initiated by amyloid beta peptides in early stages of Alzheimer's disease.
According to researchers, Alzheimer's disease may be more prevalent in women, not simply because they live longer on average, but due to the APOE E4 gene. Researchers found the APOE association was greater for women in the Tau pathway than in men. However, there was no difference between APOE expression in the amyloid pathway in women compared to men.
Researchers have discovered a direct association between astrocytes and Alzheimer's disease. In a new study, researchers report astrocytes in the brains of Alzheimer's patients produced significantly more amyloid beta than astrocytes in the brains of people without the disease.
The corn-derived MetO-rich protein, when injected, prompts the immune system to produce antibodies against the MetO component of amyloid beta. Older mice injected with the MetO-rich protein showed 50% improvement in memory compared to the control animals. The findings could be key to the development of a potential vaccine for Alzheimer's.
Amyloid-beta accumulation in the brain may contribute to deficits in circadian regulation of learning and memory during the early stages of Alzheimer's disease.
A compound used to trace amyloid plaque build up in people with Alzheimer's is not only able to extend lifespan of round worms, it also can increase quality of life, a new study reports.
