Latest

amyloid-beta

·January 1, 2020·5 min read

Objective subtle cognitive difficulties predict amyloid accumulation and neurodegeneration

Amyloid accumulation occurs faster in those who have objectively-defined cognitive difficulties than older people who are considered to be cognitively normal. Mild cognitive impairment is also associated with faster hippocampal and entorhinal cortex atrophy.

Featured Neurology Neuroscience Open Neuroscience Articles

·December 31, 2019·4 min read

Possible dementia vaccine closer after mice studies

Clinical trials for a preventative treatment for dementia was successful in mouse models. Researchers say human trials will begin in two years.

Featured Neurology Neuroscience

·December 30, 2019·3 min read

What comes first, beta-amyloid plaques or thinking and memory problems?

Subtle changes in thinking and memory may appear before, or in conjunction with, the development of amyloid plaques.

This shows a head with a swirly background

Featured Neurology Neuroscience

·November 20, 2019·4 min read

Inflammatory processes drive progression of Alzheimer’s and other brain diseases

The NLPR3 inflammasome and the inflammatory response it triggers play a critical role in the emergence of tau pathology.

Featured Neurology Neuroscience Neuroscience Videos Open Neuroscience Articles

·October 4, 2019·6 min read

Study pinpoints Alzheimer’s plaque emergence early and deep in the brain

Researchers use SWITCH technology to label amyloid plaques in mouse models of Alzheimer's disease so they could be imaged in fine detail at different ages. They were consistently able to see the plaques first emerged in deep brain structures and tracked circuits, such as the Papez memory circuit, to spread throughout the brain as the animal aged.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·October 1, 2019·3 min read

A brain protein that could put the brakes on Alzheimer’s

Reducing the expression of the protein TOM1 in mouse models of Alzheimer's disease increased the pathology, exacerbated cognitive problems, and raised levels of inflammation in the brain. Restoring TOM1 reversed the effects. Findings suggest a new therapeutic target for treating dementia.

This is an illustration of amyloid beta in neurons

Featured Neurology Neuroscience

·September 17, 2019·5 min read

Exercise could slow withering effects of Alzheimer’s

For those with mild cognitive impairment (MCI) and other risk factors for Alzheimer's disease, participating in aerobic exercise several times a week may slow neurodegeneration. Aerobic exercise reduced hippocampal atrophy in those with MCI.

This shows a woman wearing the TEMT head device

Featured Neurology Neuroscience Open Neuroscience Articles

·September 17, 2019·6 min read

Alzheimer’s memory loss reversed by new head device using electromagnetic waves

A new, non-invasive brain stimulation treatment shows promise in enhancing memories and cognitive function in those with Alzheimer's disease. Transcranial electromagnetic treatment (TEMT) increases functional connectivity within the cingulate cortex. TEMT is also able to penetrate the brain to break up amyloid-beta and tau deposits, slowing the progression of Alzheimer's disease.

Featured Neurology Neuroscience

·September 4, 2019·4 min read

‘Hunger Hormone’ Linked to Memory in Alzheimer’s Study

A study that used postmortem brain tissue samples from Alzheimer's patients and mouse models found the hunger hormone ghrelin is linked to cognitive impairments and memory loss associated with the disease.

Featured Genetics Neurology Neuroscience

·August 30, 2019·4 min read

Creation of new brain cells plays an underappreciated role in Alzheimer’s disease

Microglia may play a significant role in disrupting neurogenesis in those with Alzheimer's disease. When mice were given drugs which caused microglial cells to die, neurogenesis returned to normal.

Featured Genetics Neurology Neuroscience

·August 23, 2019·6 min read

How ‘Australian’ mutation leads to Alzheimer’s disease

The 'Australian' familial genetic mutation, L723P, causes local unfolding of the C-terminal turn of the APP TM dominant helix. The findings suggest a mechanism of pathogenesis associated with the mutation.

Featured Neurology Neuroscience Open Neuroscience Articles

·August 21, 2019·3 min read

Link between brain immune cells and Alzheimer’s disease development identified

The brain's immune cells may contribute to the development of Alzheimer's disease. Turning off microglia in specific areas of the brain prevented the formation of amyloid plaques. The findings could help pave the way for new treatments for Alzheimer's.

1 … 8 9 10 11 12 … 38

amyloid-beta

Objective subtle cognitive difficulties predict amyloid accumulation and neurodegeneration

Possible dementia vaccine closer after mice studies

What comes first, beta-amyloid plaques or thinking and memory problems?

Inflammatory processes drive progression of Alzheimer’s and other brain diseases

Study pinpoints Alzheimer’s plaque emergence early and deep in the brain

A brain protein that could put the brakes on Alzheimer’s

Exercise could slow withering effects of Alzheimer’s

Alzheimer’s memory loss reversed by new head device using electromagnetic waves

‘Hunger Hormone’ Linked to Memory in Alzheimer’s Study

Creation of new brain cells plays an underappreciated role in Alzheimer’s disease

How ‘Australian’ mutation leads to Alzheimer’s disease

Link between brain immune cells and Alzheimer’s disease development identified

Everyday Habit Changes Lowers Dementia Risk

Legalized Cannabis Does Not Increase Consumption

Disrupted Neuronal Microexons Drive Hyperarousal and Insomnia

AI Intelligence Is Not Consciousness

Subscribe