Latest

amyloid-beta

This shows a PET scan of a person with Alzheimer's

·June 11, 2019·5 min read

Education and intelligence may protect cognition’ but don’t prevent Alzheimer’s disease

Intelligence, education and participating in cognitively challenging tasks may stave off the effects of dementia for longer, but can not protect against the inevitable Alzheimer's pathology in those at risk.

This shows a virus like protein structure

Featured Neurology Neuroscience Open Neuroscience Articles

·June 11, 2019·4 min read

Memory Preserver: Researchers Develop Vaccine That Could Protect Against Alzheimer’s

Researchers have engineered a vaccine using virus-like particles that target Tau tangles in mouse models of Alzheimer's disease. Following the administration of the vaccine, the mice developed antibodies that cleared tau proteins, with the response lasting for a month. The mice also showed improvements in memory based tests and had less brain shrinkage than their peers who did not receive the vaccine. This suggests the vaccine prevented apoptosis. Researchers hope to move the vaccine to human clinical trials in the future.

Featured Neurology Neuroscience Open Neuroscience Articles

·June 3, 2019·3 min read

Brush your teeth to postpone Alzheimer’s

Brushing your teeth may be a way to stave off the development of Alzheimer's disease. Study provides new evidence of how bacteria associated with gingivitis contributes to the development of the neurodegenerative disease.

Featured Neurology Neuroscience

·May 28, 2019·5 min read

As plaque deposits increase in the aging brain, money management falters

Older adults who experience problems completing simple financial tasks, such as calculating their change, may be at increased risk of Alzheimer's disease. Problems with financial management have often been associated with later stage dementia. A new study reveals this could be one of the earliest signs of dementia and may be correlated with a build-up of amyloid plaque deposits.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·May 27, 2019·4 min read

Coat of proteins makes viruses more infectious and links them to Alzheimer’s disease

Herpes simplex virus type 1 (HSV-1) and respiratory syncytial virus (RSV) interact with biological fluids, creating a coat of proteins around the viral surface. This results in the viruses becoming more infectious and can contribute to the formation of amyloid plaques. In animal models, researchers found these viruses can bind to amyloid proteins, which aggregate into plaques that contribute to Alzheimer's disease. HSV-1 is able to accelerate the transformation of soluble amyloid proteins into amyloid plaques.

This shows the structure of amyloid beta

Featured Neurology Neuroscience

·May 17, 2019·3 min read

Identifying the molecular structure of one of Alzheimer’s stickier culprits

Researchers map a toxic protein associated with Alzheimer's disease. The study reports that pS8-AB40 acts as the alpha structure in polymorphism and has higher levels of cellular toxicity compared to other fibrils.

this shows the effect of antibiotic treatment on ab in mouse models

Featured Neurology Neuroscience Open Neuroscience Articles

·May 16, 2019·4 min read

Antibiotic treatment alleviates Alzheimer’s disease symptoms in male mice

Study reports specific gut bacteria can influence the development of Alzheimer's disease. In mouse models, long term antibiotic treatment reduced inflammation and the formation of amyloid plaques. However, the reduction was only seen in males. Additionally, the antibiotic treatment altered the activation of microglia in the male mouse models.

Featured Neurology Neuroscience Neuroscience Videos Open Neuroscience Articles

·May 15, 2019·5 min read

Artificial intelligence tool vastly scales up Alzheimer’s research

A convolutional neural network algorithm is able to process an entire whole brain slice slide with 98.7% accuracy. The technology could help speed up the diagnosis of Alzheimer's disease.

Featured Neurology Neuroscience

·May 15, 2019·2 min read

Ragweed compounds could protect nerve cells from Alzheimer’s

Compounds derived from common ragweed may help in the fight against Alzheimer's disease. Researchers report when two of the most active compounds were added to a sample of neurons producing amyloid beta, 20% more cells survived than without exposure.

This shows someone carrying out a blood sample analysis

Featured Neurology Neuroscience Open Neuroscience Articles

·May 5, 2019·3 min read

New early detection blood test for Alzheimer’s

A new two-tier diagnostic blood test which evaluates both amyloid beta and tau, can help detect Alzheimer's disease in presymptomatic patients.

Featured Genetics Neurology Neuroscience

·May 1, 2019·9 min read

Alzheimer’s disease is a ‘double-prion disorder’

Self-propagating amyloid and tau act as prions in the pathology of Alzheimer's disease. Higher levels of the prions in human brain samples were strongly correlated with early onset of Alzheimer's and death at a younger age.

Featured Genetics Neurology Neuroscience

·May 1, 2019·5 min read

Restoring brain function in mice with symptoms of Alzheimer’s disease

Senolytic drugs administered to mice reduced senescent cells around amyloid plaques by more than 90% and decreased neuroinflammation by 50%. Mice treated with the drug combination also showed improvements in spatial memory, compared to other Alzheimer's model mice who received no treatment. The findings could have positive implications for the treatment of Alzheimer's disease in people with the condition.

1 … 10 11 12 13 14 … 38

amyloid-beta

Education and intelligence may protect cognition’ but don’t prevent Alzheimer’s disease

Memory Preserver: Researchers Develop Vaccine That Could Protect Against Alzheimer’s

Brush your teeth to postpone Alzheimer’s

As plaque deposits increase in the aging brain, money management falters

Coat of proteins makes viruses more infectious and links them to Alzheimer’s disease

Identifying the molecular structure of one of Alzheimer’s stickier culprits

Antibiotic treatment alleviates Alzheimer’s disease symptoms in male mice

Artificial intelligence tool vastly scales up Alzheimer’s research

Ragweed compounds could protect nerve cells from Alzheimer’s

New early detection blood test for Alzheimer’s

Alzheimer’s disease is a ‘double-prion disorder’

Restoring brain function in mice with symptoms of Alzheimer’s disease

Chickadees Sneak Around for Brains, Not Just Brawn

Retinal Photos and AI Predict Early Alzheimer’s Risk

AI Voice Scams Weaponize Vocal Timbre to Trick Our Trust

Senescent Cells Are Essential for Building the Brain’s Barriers

Subscribe