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amyloid-beta

This shows two brain tissue samples, one with amyloid and another after treatment to remove the amyloid

Featured Genetics Neurology Neuroscience

·February 21, 2021·6 min read

Protein Linked to Alzheimer’s and Strokes Cleared From Brain Blood Vessels

An antibody called HAE-4 targets APOE and removes Alzheimer's related amyloid plaques in mouse models. The antibody improves blood vessel function in the brain without raising the risk of brain bleeds.

This shows someone holding an older lady's hands

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·February 8, 2021·4 min read

Brain Protein That Causes Alzheimer’s Also Protects Against the Disease

Amyloid-beta38 may have protective benefits against Alzheimer's disease, researchers report.

This is a computer generated image of a brain made up of computerized neurons

Featured Neurology Neuroscience

·January 21, 2021·4 min read

Study Shows the Relationship Between Surgery and Alzheimer’s Disease

Major surgery can trigger different patterns of cognitive alterations depending on previous presence, or absence, of Alzheimer's pathologies.

Featured Neurology Neuroscience

·October 12, 2020·3 min read

Brain Regions With Impaired Blood Flow Have Higher Tau Levels

Impaired blood flow to specific areas of the brain coincides with Tau buildup in Alzheimer's patients. As cognition declines, the relationship between vascular dysfunction and Tau accumulation strengthens.

Featured Neurology Neuroscience

·September 28, 2020·5 min read

Link Between Sleep Apnea and Alzheimer’s Confirmed

Amyloid plaques form in the same location and spread in the same way in the brains of people with both obstructive sleep apnea and Alzheimer's disease.

Featured Neurology Neuroscience Open Neuroscience Articles

·September 3, 2020·6 min read

How We Sleep Today May Forecast When Alzheimer’s Disease Begins

Current sleep patterns could help determine your risk of developing Alzheimer's disease as you age. People who experience more fragmented sleep and less non-REM slow-wave sleep are more likely to have increased levels of amyloid-beta.

Neuroscience

·September 2, 2020·4 min read

Inflammation Linked to Alzheimer’s Disease Development

IFITM3, a protein that plays a role in the immune response to pathogens, also plays a key role in the accumulation of amyloid-beta plaques. As IFITM3 directly affects plaque formation, researchers suggest both viral and bacterial infections could increase the risk of Alzheimer's development.

Featured Neurology

·September 1, 2020·4 min read

Estrogen Replacement May Protect Against Alzheimer’s Disease in Women

Early postmenopausal estrogen replacement therapy may protect some women from developing Alzheimer's disease.

This shows someone performing a lab experiment

Featured Neurology Neuroscience Open Neuroscience Articles

·August 18, 2020·3 min read

Links Found Between Diabetes Blood Markers and Alzheimer’s Pathology

Study reveals a link between amyloid-beta accumulation in the brain and lower levels of insulin and insulin resistance.

Featured Neurology Open Neuroscience Articles

·August 11, 2020·3 min read

Right Under Your Nose: A More Convenient Way to Diagnose Alzheimer’s

Analyzing nasal discharge could be a new tool in diagnosing and monitoring the progression of Alzheimer's disease. Researchers found certain Alzheimer's related proteins can be detected in nasal discharge.

Featured Neurology

·July 27, 2020·3 min read

Temporary Salt Crystals May Provide a Permanent Solution to Alzheimer’s

Salt crystals can precipitate at low concentrations due to local density fluctuations. Their repeated precipitation dissolution behavior promotes amyloid-beta peptide aggregation.

Featured Neurology

·July 20, 2020·4 min read

Oxytocin Could Be Used to Treat Cognitive Disorders Like Alzheimer’s

Oxytocin, the so-called "love hormone," could help to treat cognitive disorders, including Alzheimer's disease. Researchers demonstrated oxytocin reversed the effects of amyloid-beta on hippocampal LTP in mice. The findings suggest oxytocin could be used as a therapeutic for the treatment of Alzheimer's disease and other dementias.