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amyloid-beta

This shows an outline of a woman's head, brain and birds flowing in it

Featured Neurology Neuroscience

·March 25, 2021·4 min read

Women Accumulate Alzheimer’s-Related Protein Faster

Study reports tau accumulation in the temporal lobe was 75% higher in women than men.

Featured Neurology Neuroscience Visual Neuroscience

·March 10, 2021·5 min read

Alzheimer’s Disease Protein Linked to Common Sight Loss

Exposing retinal pigment epithelium cells in mouse models to amyloid-beta resulted in retinal pathologies similar to those seen in human age-related macular degeneration.

Featured Neurology Neuroscience

·February 25, 2021·2 min read

How Amyloid Beta Contributes to Loss of Smell in Alzheimer’s Disease

Regions of the olfactory system in mice with higher amyloid beta expression exhibited lower activation of olfactory sensory neurons and decreased odor detection.

This shows a schematic of synapses from the study

Electrophysiology Featured Neurology Neuroscience

·February 24, 2021·4 min read

Uncovering the Molecular Mechanism Behind Synapse Loss in Alzheimer’s Disease

Over-expression of the synaptic protein RAPGEF2 drives synaptic loss associated with Alzheimer's disease.

This shows two brain tissue samples, one with amyloid and another after treatment to remove the amyloid

Featured Genetics Neurology Neuroscience

·February 21, 2021·6 min read

Protein Linked to Alzheimer’s and Strokes Cleared From Brain Blood Vessels

An antibody called HAE-4 targets APOE and removes Alzheimer's related amyloid plaques in mouse models. The antibody improves blood vessel function in the brain without raising the risk of brain bleeds.

This shows someone holding an older lady's hands

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·February 8, 2021·4 min read

Brain Protein That Causes Alzheimer’s Also Protects Against the Disease

Amyloid-beta38 may have protective benefits against Alzheimer's disease, researchers report.

This is a computer generated image of a brain made up of computerized neurons

Featured Neurology Neuroscience

·January 21, 2021·4 min read

Study Shows the Relationship Between Surgery and Alzheimer’s Disease

Major surgery can trigger different patterns of cognitive alterations depending on previous presence, or absence, of Alzheimer's pathologies.

Featured Neurology Neuroscience

·October 12, 2020·3 min read

Brain Regions With Impaired Blood Flow Have Higher Tau Levels

Impaired blood flow to specific areas of the brain coincides with Tau buildup in Alzheimer's patients. As cognition declines, the relationship between vascular dysfunction and Tau accumulation strengthens.

Featured Neurology Neuroscience

·September 28, 2020·5 min read

Link Between Sleep Apnea and Alzheimer’s Confirmed

Amyloid plaques form in the same location and spread in the same way in the brains of people with both obstructive sleep apnea and Alzheimer's disease.

Featured Neurology Neuroscience Open Neuroscience Articles

·September 3, 2020·6 min read

How We Sleep Today May Forecast When Alzheimer’s Disease Begins

Current sleep patterns could help determine your risk of developing Alzheimer's disease as you age. People who experience more fragmented sleep and less non-REM slow-wave sleep are more likely to have increased levels of amyloid-beta.

Neuroscience

·September 2, 2020·4 min read

Inflammation Linked to Alzheimer’s Disease Development

IFITM3, a protein that plays a role in the immune response to pathogens, also plays a key role in the accumulation of amyloid-beta plaques. As IFITM3 directly affects plaque formation, researchers suggest both viral and bacterial infections could increase the risk of Alzheimer's development.