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amyloid-beta

·June 15, 2021·4 min read

Brain Cell Membranes’ Lipids May Play Big Role in Alzheimer’s Progression

Study reveals the significant role lipids play in regulating the amyloid pathway protein C99 and the progression of Alzheimer's disease.

Featured Neurology Neuroscience

·June 14, 2021·3 min read

A New Model of Alzheimer’s Progression

A new model of Alzheimer's progression highlights the link between glial cells, toxic protein buildup, and neurodegeneration.

Featured Neurology Neuroscience Open Neuroscience Articles

·June 1, 2021·3 min read

Role of Sleep-Related Brain Activity in Clearing Toxic Proteins and Preventing Alzheimer’s Disease

The connection between brain activity during sleep and cerebrospinal fluid flow was reduced in those with risk factors for dementia and those with Alzheimer's disease than in the healthy control group.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 18, 2021·4 min read

Gene That Could Help Prevent or Delay Onset of Alzheimer’s Disease Identified

Boosting the expression of the ABCC1 gene may not only reduce amyloid plaques in the brain, it might also delay the onset of Alzheimer's disease.

This shows AB plaques surrounded by microglia

Featured Genetics Neurology Neuroscience

·April 16, 2021·5 min read

Some Alzheimer’s Plaques May Be Protective, Not Destructive

Microglia creates dense-core plaques which help to clear away more wispy plaques from neurons, preventing cell death. Findings suggest the dense-core plaques play a defensive role in protecting the brain from the ravages of neurodegenerative diseases, such as Alzheimer's.

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·April 12, 2021·5 min read

Imbalance in Gum Bacteria Linked to Alzheimer’s Disease Biomarker

An increase in bad gum bacteria and a decrease in good bacteria is associated with amyloid-beta in cerebral spinal fluid samples of older adults. The findings add to the growing body of evidence linking periodontal disease to the development of Alzheimer's.

Featured Genetics Neurology Neuroscience

·April 9, 2021·3 min read

Aluminum Is Intricately Associated With the Neuropathology of Familial Alzheimer’s Disease

Study reveals aluminum is co-located with the tau protein in people with familial Alzheimer's disease.

Featured Genetics Neurology Neuroscience

·April 2, 2021·5 min read

Unusual Mechanism in Rare Mutation Associated With Alzheimer’s Uncovered

The S198P mutation causes APP to fold more quickly, allowing amyloid-beta peptides to produce from mature APP at a more rapid rate than from APP that does not contain the genetic mutation. The findings shed new light on genetic mutations associated with Alzheimer's disease.

This shows an outline of a woman's head, brain and birds flowing in it

Featured Neurology Neuroscience

·March 25, 2021·4 min read

Women Accumulate Alzheimer’s-Related Protein Faster

Study reports tau accumulation in the temporal lobe was 75% higher in women than men.

Featured Neurology Neuroscience Visual Neuroscience

·March 10, 2021·5 min read

Alzheimer’s Disease Protein Linked to Common Sight Loss

Exposing retinal pigment epithelium cells in mouse models to amyloid-beta resulted in retinal pathologies similar to those seen in human age-related macular degeneration.

Featured Neurology Neuroscience

·February 25, 2021·2 min read

How Amyloid Beta Contributes to Loss of Smell in Alzheimer’s Disease

Regions of the olfactory system in mice with higher amyloid beta expression exhibited lower activation of olfactory sensory neurons and decreased odor detection.