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amyloid-beta

Featured Genetics Neurology Neuroscience

·December 22, 2021·7 min read

New Alzheimer’s Prevention Trial in Young People

A new international clinical trial has been launched with an aim of preventing Alzheimer's disease in people with a genetic disposition who are likely to develop the disease at a younger age.

Featured Genetics Neurology Neuroscience

·December 20, 2021·2 min read

Twins Study Indicates Environmental Factors Significant in Alzheimer’s Pathology

Genes only play a moderate role in the accumulation of amyloid beta in the brain.

This shows microglia in the brain of alzheimer's mouse models

Featured Neurology Neuroscience

·December 2, 2021·5 min read

Immune Cells in the Brain Play Key Role in Relationship Between Gut Microbes and Amyloid Beta Deposits

Microglia, a key immune cell in the brain, appears to mediate the relationship between the gut microbiome and amyloid-beta deposits in male mouse models of Alzheimer's disease.

This shows a model of a head and a brain

Featured Neurology Neuroscience

·November 27, 2021·5 min read

New Framework for Analyzing Alzheimer’s Disease Identifies Not One Form, but Three

A new framework reveals Alzheimer's disease is far more complex than previously believed. Rather than being a disease where the same causes produce the same outcomes, researchers found three different models for the disease, each with its own characterizations and dynamics.

This shows an older lady getting out of bed

Featured Neurology Neuroscience

·November 19, 2021·3 min read

Disrupted Circadian Regulation of Cognition in Alzheimer’s Disease

Amyloid-beta accumulation in the brain may contribute to deficits in circadian regulation of learning and memory during the early stages of Alzheimer's disease.

This shows an older lady with her hands crossed over her knees

Featured Neurology Neuroscience Open Neuroscience Articles

·November 15, 2021·5 min read

New Approach Provides Potential Vaccine and Treatment for Alzheimer’s

A newly developed antibody-based treatment and protein-based vaccine reduced Alzheimer's symptoms in mouse models, researchers report.

this shows a brain drawn as a blue print

Featured Neurology Neuroscience Open Neuroscience Articles

·November 6, 2021·6 min read

Restoring Normal Sleep Reduces Amyloid-Beta Accumulation in Mouse Model of Alzheimer’s Disease

Restoring normal sleep patterns by activating the thalamic reticular nucleus with chemogenetics reduced the accumulation of amyloid-beta plaques in the brains.

Featured Neurology Neuroscience

·November 6, 2021·5 min read

Sleeping Longer Than 6.5 Hours a Night Associated With Cognitive Decline

Older adults who sleep less than 4.5 hours, or more than 6.5 hours per night and who experience sleep disruptions are at greater risk of cognitive decline, researchers report.

Featured Genetics Neurology Neuroscience

·November 5, 2021·4 min read

The Role of Gene Associated With Alzheimer’s Disease in Brain’s Immune Cells

Deleting ABI3, a gene associated with Alzheimer's disease, significantly increased amyloid-beta accumulation in the brain and decreased the amount of microglia around amyloid-plaques, researchers report.

Featured Neurology Neuroscience

·October 29, 2021·4 min read

Cause of Alzheimer’s Progression in the Brain Identified

New findings contradict the existing thought that Alzheimer's starts from a single point in the brain and causes a chain reaction that leads to cell death. Instead, a new study reports, Alzheimer's disease reaches different brain regions early on. The speed by which the disease kills brain cells in these regions directly impacts the progression of Alzheimer's.

Featured Neuroscience Open Neuroscience Articles Psychology

·October 9, 2021·5 min read

Amyloid Beta and Serotonin May Be Keys to Predicting Who Develops Late-Life Depression

Increased accumulation of amyloid beta and a reduction of serotonin in the brains of older adults was associated with higher risks for developing depression later in life.