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amyloid-beta

Featured Neurology Neuroscience Open Neuroscience Articles

·August 19, 2019·5 min read

New insights into what may go awry in brains of Alzheimer’s patients

Amyloid beta may be less harmful than previously thought. However, an age-damaged version of the protein may be more harmful.

This shows a researcher performing analyzes of blood work

Featured Neurology Neuroscience

·August 2, 2019·6 min read

Blood test 94% accurate at identifying Alzheimer’s before symptoms appear

A new blood test for Alzheimer's disease is up-to 94% accurate at predicting dementia before symptoms appear. The test's accuracy is increased when genetic predisposition and age are taken into account. The new test may eventually replace PET neuroimaging, currently considered the gold standard, for early detection of Alzheimer's.

Featured Neuroscience

·July 31, 2019·6 min read

Novel discovery of links between liver dysfunction and Alzheimer’s disease

A link between liver dysfunction and Alzheimer's disease has been discovered. The findings add to the understanding of the role metabolic dysfunction plays in the neurodegenerative disease.

This shows an old couple walking down a country lane

Featured Neurology Neuroscience

·July 16, 2019·2 min read

Risk and progression of Alzheimer’s disease differ by gender

The risk of developing Alzheimer's disease is increased, and progression more rapid in women due to larger brain-wide accumulation and acceleration in the spread of tau.

Featured Genetics Neurology Neuroscience

·July 9, 2019·4 min read

Sorting protein in neurons defends against neurodegenerative disease

VPS35 is a novel critical component of tau metabolism and the pathology of neurodegenerative diseases.

This shows a researcher analyzing a blood sample

Featured Neurology Neuroscience Open Neuroscience Articles

·June 29, 2019·5 min read

New blood test for detecting Alzheimer’s disease to undergo trial

A new blood test to detect biomarkers for Alzheimer's disease is set to undergo trials in the Fall. The test will be able to identify traces of amyloid beta in blood samples with a high degree of accuracy.

This shows an old lady sitting on a bench

Featured Neurology Neuroscience

·June 28, 2019·3 min read

Study connects low social engagement to amyloid levels and cognitive decline

An association has been discovered between cognitive decline and social engagement in older adults. Older people who are less socially active have a greater accumulation of amyloid beta and increased cognitive decline over a three-year span, compared to more socially active peers.

This shows a brain with tau deposits marked

Featured Neurology Neuroscience

·June 27, 2019·8 min read

Disrupted sleep in one’s 50s, 60s raises risk of Alzheimer’s disease

Sleep disruptions during middle age may be a potential biomarker for developing Alzheimer's disease later in life. Researchers found those who experienced sleep problems in their 40s and 50s had more amyloid beta accumulation in their brains later in life. Those whose sleep problems started in their 50s and 60s had increased levels of tau. Additionally, higher levels of tau were discovered in the brains of those who lacked synchronized brain waves associated with a good night's sleep.

This shows amyloid beta, tau and microglia

Featured Genetics Neurology Neuroscience

·June 24, 2019·4 min read

Alzheimer’s missing link ID’d, answering what tips brain’s decline

Study in mice and humans reveals reinforcing the activity of microglia could slow, or potentially halt, the proliferation of Tau tangles in Alzheimer's disease.

Featured Neurology Neuroscience

·June 23, 2019·2 min read

Squeezing of blood vessels may contribute to cognitive decline in Alzheimer’s

Capillary constriction caused by amyloid beta restricts cerebral blood flow in mouse models of Alzheimer's disease. Inhibiting the capillary constriction may potentially reduce some of the neurodegenerative features of Alzheimer's.

This shows brain scans of the hippocampus during sleep

Featured Neurology Neuroscience

·June 17, 2019·3 min read

Sleep history predicts late-life Alzheimer’s pathology

Your sleep history during middle age may predict Alzheimer's pathology later in life. A decrease in sleep quality between 50 and 70 years of age is associated with higher levels of tau and amyloid beta in the brain. Changes in brain activity and quality of sleep could be a biomarker for Alzheimer's disease.

Featured Neurology Neuroscience Open Neuroscience Articles

·June 14, 2019·4 min read

Modified protein can prevent Alzheimer’s disease in mice

Researchers injected a modified segment of the amyloid precursor protein into mouse models of Alzheimer's disease. The treatment appeared to reverse a number of the cognitive and memory problems associated with the neurodegenerative disease.