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amyloid-beta

·September 4, 2019·4 min read

‘Hunger Hormone’ Linked to Memory in Alzheimer’s Study

A study that used postmortem brain tissue samples from Alzheimer's patients and mouse models found the hunger hormone ghrelin is linked to cognitive impairments and memory loss associated with the disease.

Featured Genetics Neurology Neuroscience

·August 30, 2019·4 min read

Creation of new brain cells plays an underappreciated role in Alzheimer’s disease

Microglia may play a significant role in disrupting neurogenesis in those with Alzheimer's disease. When mice were given drugs which caused microglial cells to die, neurogenesis returned to normal.

Featured Genetics Neurology Neuroscience

·August 23, 2019·6 min read

How ‘Australian’ mutation leads to Alzheimer’s disease

The 'Australian' familial genetic mutation, L723P, causes local unfolding of the C-terminal turn of the APP TM dominant helix. The findings suggest a mechanism of pathogenesis associated with the mutation.

Featured Neurology Neuroscience Open Neuroscience Articles

·August 21, 2019·3 min read

Link between brain immune cells and Alzheimer’s disease development identified

The brain's immune cells may contribute to the development of Alzheimer's disease. Turning off microglia in specific areas of the brain prevented the formation of amyloid plaques. The findings could help pave the way for new treatments for Alzheimer's.

Featured Neurology Neuroscience Open Neuroscience Articles

·August 19, 2019·5 min read

New insights into what may go awry in brains of Alzheimer’s patients

Amyloid beta may be less harmful than previously thought. However, an age-damaged version of the protein may be more harmful.

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Featured Neurology Neuroscience

·August 2, 2019·6 min read

Blood test 94% accurate at identifying Alzheimer’s before symptoms appear

A new blood test for Alzheimer's disease is up-to 94% accurate at predicting dementia before symptoms appear. The test's accuracy is increased when genetic predisposition and age are taken into account. The new test may eventually replace PET neuroimaging, currently considered the gold standard, for early detection of Alzheimer's.

Featured Neuroscience

·July 31, 2019·6 min read

Novel discovery of links between liver dysfunction and Alzheimer’s disease

A link between liver dysfunction and Alzheimer's disease has been discovered. The findings add to the understanding of the role metabolic dysfunction plays in the neurodegenerative disease.

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Featured Neurology Neuroscience

·July 16, 2019·2 min read

Risk and progression of Alzheimer’s disease differ by gender

The risk of developing Alzheimer's disease is increased, and progression more rapid in women due to larger brain-wide accumulation and acceleration in the spread of tau.

Featured Genetics Neurology Neuroscience

·July 9, 2019·4 min read

Sorting protein in neurons defends against neurodegenerative disease

VPS35 is a novel critical component of tau metabolism and the pathology of neurodegenerative diseases.

This shows a researcher analyzing a blood sample

Featured Neurology Neuroscience Open Neuroscience Articles

·June 29, 2019·5 min read

New blood test for detecting Alzheimer’s disease to undergo trial

A new blood test to detect biomarkers for Alzheimer's disease is set to undergo trials in the Fall. The test will be able to identify traces of amyloid beta in blood samples with a high degree of accuracy.

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Featured Neurology Neuroscience

·June 28, 2019·3 min read

Study connects low social engagement to amyloid levels and cognitive decline

An association has been discovered between cognitive decline and social engagement in older adults. Older people who are less socially active have a greater accumulation of amyloid beta and increased cognitive decline over a three-year span, compared to more socially active peers.

This shows a brain with tau deposits marked

Featured Neurology Neuroscience

·June 27, 2019·8 min read

Disrupted sleep in one’s 50s, 60s raises risk of Alzheimer’s disease

Sleep disruptions during middle age may be a potential biomarker for developing Alzheimer's disease later in life. Researchers found those who experienced sleep problems in their 40s and 50s had more amyloid beta accumulation in their brains later in life. Those whose sleep problems started in their 50s and 60s had increased levels of tau. Additionally, higher levels of tau were discovered in the brains of those who lacked synchronized brain waves associated with a good night's sleep.