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neurogenesis

·February 28, 2020·4 min read

Newly identified cellular trash removal program helps create new neurons

Vimentin, a cellular filament, helps neural stem cells to clear damaged and clumped proteins, assisting in neurogenesis.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·February 12, 2020·5 min read

Gene associated with autism also controls growth of the embryonic brain

In normally developing mice, the autism-associated Foxp1 gene was activated earlier than previously believed. This occurred during the period when apical radial glia was beginning to expand in numbers and generate a subset of neurons found deep in the developing brain. Mice lacking Foxp1 had fewer apical radial glia at the early stages of brain development.

Electrophysiology Featured Neuroscience Open Neuroscience Articles

·February 6, 2020·3 min read

Brain tissue stiffness is crucial for neurogenesis

Researchers define the proteome of neural stem cell niches and the entire set of expressed proteins. The findings shed light on key regulators of neurogenesis.

This shows microspheres with neural growth factor

Featured Neurology Neuroscience

·January 22, 2020·3 min read

Synthetic nerve conduit bridges the gap in arm nerve repair

A new synthetic conduit can bridge large nerve gaps by guiding the regrowth of neurons. When implanted into the arms of macaques with nerve defects in their arms, the conduit boosted neurogenesis and the nerve's ability to conduct signals for a year.

Featured Genetics Neuroscience

·January 20, 2020·2 min read

A new role for neurogenesis

Dentate gyrus neurogenesis acts to replace lost neurons and restore function following massive neuron loss.

Electrophysiology Featured Genetics Neuroscience Open Neuroscience Articles

·January 9, 2020·4 min read

Rejuvenating the brain: More stem cells improve learning and memory of old mice

Critical aspects of hippocampal function can be reversed in old age, or compensated for throughout life, with the help of neural stem cells.

Featured Neurology Neuroscience

·December 26, 2019·3 min read

High fat diet impairs new neuron creation in female mice

Female mice exposed to a high-fat diet have limited hippocampal neurogenesis. The findings may explain why women are at higher risk of developing dementia than men.

Featured Genetics Neuroscience

·December 9, 2019·2 min read

The genetic signature of memory

Cortical and subcortical memory regions exhibit distinct genetic signatures that reflect potential differences in health and disease.

Featured Neuroscience Open Neuroscience Articles

·November 14, 2019·4 min read

Bacteria in the gut may alter aging process

Transplanting gut microbiota from older mice to younger germ-free mice increased hippocampal neurogenesis and intestinal growth.

Featured Genetics Neurology Neuroscience

·August 30, 2019·4 min read

Creation of new brain cells plays an underappreciated role in Alzheimer’s disease

Microglia may play a significant role in disrupting neurogenesis in those with Alzheimer's disease. When mice were given drugs which caused microglial cells to die, neurogenesis returned to normal.

Featured Neuroscience

·August 29, 2019·6 min read

Machine learning algorithm can’t distinguish these lab mini-brains from preemie babies

Machine learning is unable to tell the difference in brain activity between a lab-grown mini-brain and that of a preterm infant who has reached full-term.