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neurogenesis

This shows how the AI discovered the mutations

·May 27, 2019·5 min read

New causes of autism found in ‘junk’ DNA

Using artificial intelligence, researchers discover mutations in noncoding regions of the human genome that may result in autism. The noncoding mutations are associated with altered gene regulation in children with ASD. Additionally, the mutations affect gene expression in the brain and genes already linked to autism, such as those responsible for neuron development and migration.

Featured Genetics Neurology Neuroscience

·May 24, 2019·4 min read

New neurons form in the brain into tenth decade of life, even in people with Alzheimer’s

Hippocampal neurogenesis continues to occur well into old age, and in those with Alzheimer's disease. Researchers found evidence of neurogenesis in people up to the age of 99. While neurogenesis continues to occur in those with Alzheimer's disease, it is significantly reduced compared to those who have normal cognitive function.

Featured Genetics Neuroscience

·May 14, 2019·8 min read

Blocking protein curbs memory loss in old mice

Blocking VCAM1 increased neurogenesis, and reduced microglia reactivity in the hippocampus of older mice.

This shows a person holding his tummy as if in pain

Featured Genetics Neuroscience Psychology

·May 7, 2019·7 min read

Study explains why a moody gut often accompanies depression

Mice with a genetic mutation linked to severe depression had impaired ability for neurons in the gut and brain to create serotonin. The reduction of serotonin in the gut led to a deterioration in the gut's lining, slowing the movement of contents through the GI tract and resulting in constipation. However, treatment with 5-HTP increased neurogenesis in the gut, restoring normal function.

Featured Genetics Neuroscience

·May 5, 2019·3 min read

Connecting neurons in the brain

The phosphatase Prl-1 plays a key role in specifying where to form the highest density of synaptic connections on a neuron.

Featured Genetics Neurology Neuroscience

·April 5, 2019·3 min read

Parkinson’s clues seen in tiny fish could aid quest for treatments

Zebrafish study reveals how key dopaminergic neurons, which are damaged as a result of Parkinson's disease, can be regenerated. Researchers report the immune system plays a critical role in the process.

Featured Genetics Neuroscience

·March 28, 2019·3 min read

Single Population of Stem Cells Contributes to Lifelong Hippocampal Neurogenesis: Mouse Study

The findings support a continuous model of neurogenesis throughout development and adulthood.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·February 20, 2019·4 min read

Young Bone Marrow Rejuvenates Aging Brains: Mouse Study

Researchers report transplanting bone marrow from young mice to older mice helps to preserve memory and learning skills. If the findings can be replicated in humans, researchers believe new therapies can be devised to help combat disorders associated with brain aging.

Featured Neuroscience Open Neuroscience Articles

·February 7, 2019·4 min read

Simple Drug Combination Creates New Neurons from Neighboring Cells

Researchers have identified a small set of molecules that can convert glial cells into new neurons. The finding could help develop new treatments for Alzheimer's disease and brain injuries.

Featured Neuroscience Open Neuroscience Articles

·January 28, 2019·4 min read

Stress and Dream Sleep Linked to Pathways of Neuron Death and Survival

According to a new study, the consequence of daily stress is linked to an increase in REM sleep. Researchers report the increase is associated with genes involved in apoptosis and cell survival. The findings shed light on how stress leads to mood disorders, and how changes in sleep contribute to this.

Featured Neuroscience Open Neuroscience Articles

·January 25, 2019·3 min read

Lessons Learned From the Adult Neurogenesis Debate

A new paper looks at the controversies surrounding adult neurogenesis.

Featured Genetics Neurology

·January 23, 2019·4 min read

Old Cells Repair Damage in Brains of Those with Multiple Sclerosis

Researchers discovered oligodendrocyte neurogenesis is limited in the brains of patients with Multiple Sclerosis. However, oligodendrocytes that survive the autoimmune attack associated with MS may be able to form new myelin.