Brain cells exposed to blood taken from COVID-19 patients with delirium showed a decrease in neurogenesis and an increase in cell death. The findings also indicate a key role for cytokines produced in the immune system during infection and shed light on the molecular mechanisms of COVID-19 related delirium.
Oxytocin, a hormone connected with bonding and love, could help to heal damage following a heart attack. Researchers found oxytocin stimulates stem cells from the heart's outer layer and migrates into the middle layer where it develops into muscle cells that generate heart contractions. This could be used to promote the regeneration of heart cells following a heart attack.
Axolotls have the ability to regenerate brain areas following an injury. Researchers have mapped cell types and genes associated with neurodegeneration in the axolotl brain, discovering some similarities in the human brain. The findings could pave the way for new neurodegenerative therapies.
Increasing neurogenesis by deleting the Bax gene in mouse models of Alzheimer's improved the animals' performance in tests measuring spatial recognition and contextual memory.
A new study of the hippocampus reveals immature, plastic neurons are present in significant numbers during the entire lifespan. The findings shed new light on neuroplasticity.
Researchers used optogenetics techniques to stimulate specific brain areas to increase neurogenesis and the production of neural stem cells to improve memory, cognition, and emotional processing in animal models.
INSR, a protein essential for insulin activity, plays a critical role in stem cell longevity. Additionally, inactivating INSR in glioblastoma brain cancer stem cells inhibits the growth of primitive tumor forming cells.