After discovering the importance of cell metabolism in neurogenesis, researchers were able to increase the number of neurons in the brains of adult and elderly mice.
A newly developed blood-based test reveals changes in hippocampal neurogenesis up to 3.5 years before a clinical diagnosis of Alzheimer's disease.
High-frequency repetitive transcranial magnetic stimulation (rTMS) activates MAP2K signaling and enhanced axon regeneration and functional recovery following spinal cord injury.
In the olfactory bulb, levels of oxytocin rise and peak when new neurons incorporate themselves into neural networks. The findings shed new light on adult neurogenesis and brain plasticity.
A new hybrid of biomaterial nanoparticles in conjunction with existing methods of tissue regeneration was successfully synthesized to promote and regenerate tissue following spinal cord injury. The new method has the potential to treat spinal cord injuries.
Brain cells exposed to blood taken from COVID-19 patients with delirium showed a decrease in neurogenesis and an increase in cell death. The findings also indicate a key role for cytokines produced in the immune system during infection and shed light on the molecular mechanisms of COVID-19 related delirium.
A newly discovered second stem cell population in the mouse brain is responsible for the production of new neurons in the olfactory bulb of adult mice.
Oxytocin, a hormone connected with bonding and love, could help to heal damage following a heart attack. Researchers found oxytocin stimulates stem cells from the heart's outer layer and migrates into the middle layer where it develops into muscle cells that generate heart contractions. This could be used to promote the regeneration of heart cells following a heart attack.
Axolotls have the ability to regenerate brain areas following an injury. Researchers have mapped cell types and genes associated with neurodegeneration in the axolotl brain, discovering some similarities in the human brain. The findings could pave the way for new neurodegenerative therapies.
Increasing neurogenesis by deleting the Bax gene in mouse models of Alzheimer's improved the animals' performance in tests measuring spatial recognition and contextual memory.
Researchers discuss current studies about cognitive rejuvenation and discuss steps we can take to help protect our brains as we age.
A new study of the hippocampus reveals immature, plastic neurons are present in significant numbers during the entire lifespan. The findings shed new light on neuroplasticity.
