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neurogenesis

Featured Neuroscience Open Neuroscience Articles

·August 20, 2019·4 min read

Alzheimer’s drug reverses brain damage from adolescent alcohol exposure

Donepezil, a drug routinely administered to slow cognitive decline in Alzheimer's disease, shows promise in treating damage caused to the brain by adolescent alcohol exposure. The drug reverses neuroinflammation and neuron damage in rats exposed to alcohol during adolescence.

Featured Genetics Neuroscience

·August 14, 2019·3 min read

Scientists reverse aging process in rat brain stem cells

Removing Piezo1 from the surface of aged brain stem cells caused the cells to become rejuvenated and regain their normal regenerative function.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles Psychology

·August 9, 2019·3 min read

How chronic stress causes brain damage

Chronic stress causes autophagy in adult hippocampal neural stem cells. This results in a decline of hippocampal neurogenesis. Cognitive deficits and mood disorders that arise as a result of chronic stress are a result of autophagic death of hippocampal neural stem cells.

Featured Genetics Neuroscience Open Neuroscience Articles

·July 25, 2019·4 min read

To become, or not to become… a neuron

Bcl6 acts as a driver of neurogenic transition by directly silencing a selection of genes that belong to multiple extrinsic pathways promoting self-renewal. Bcl6 is only expressed in specific subsets of neurons and progenitor cells during brain development.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·July 22, 2019·4 min read

Exosomes may hold the answer to treating and diagnosing developmental brain disorders

Exosomes carry signaling information required to regulate neural circuit development.

Featured Neurology Neuroscience

·July 15, 2019·2 min read

Reducing seizures by removing newborn neurons

Removing new neurons generates as a result of neurogenesis following brain injury reduced seizure activity in mouse models of mesial temporal lobe epilepsy.

Featured Neurology Neuroscience Open Neuroscience Articles

·July 11, 2019·5 min read

First step to induce self-repair in the central nervous system

Severed axonal segments signal to Schwann cells to begin actin sphere formation and axon disintegration. If the process is disrupted, axon disintegration is slowed and axon fragments impair nerve regeneration.

Featured Genetics Neurology Neuroscience

·July 3, 2019·6 min read

Immune cells invade aging brains, disrupt new nerve cell formation

Intrusive T cells have been discovered in the brain's neurogenic niches of older mice and humans. Findings suggest the T cells impair neurogenesis.

Featured Neuroscience Open Neuroscience Articles

·July 2, 2019·4 min read

Short bout of exercise enhances brain function

Short bursts of exercise, equivalent to a pick-up game of basketball, boosts the function of a gene that increases dendritic spines in the hippocampus, helping to improve memory and learning.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·June 25, 2019·5 min read

Alzheimer’s mouse model seizures disrupt adult neurogenesis

Seizures associated with Alzheimer's disease in both animal models and humans alter hippocampal neurogenesis. Treating mice with antiseizure medications normalized neurogenesis and improved spatial discrimination.

Featured Genetics Neuroscience Open Neuroscience Articles

·June 18, 2019·3 min read

Dormant neural stem cells in fruit flies activate to generate new brain cells

Awakening dormant stem cells could stimulate the growth of new neurons. The findings could have significant implications for the treatment of neurodegenerative diseases.

Featured Neurology Neuroscience

·May 27, 2019·3 min read

Broken brain cells repaired in dementia mouse model

Chemically activating neurons and placing mice in stimulating environments reverses alterations and restores some neural connectivity in frontotemporal dementia. If translated into humans, the findings could help develop new treatments for fighting the effects of dementia in the elderly.

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