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neurodegeneration

·November 14, 2013·3 min read

New Study Identifies Genes Uniquely Expressed by the Brain’s Immune Cells

Researchers use a novel sequencing method to identify a group of genes used by microglia to sense pathogenic organisms, toxins and damaged neurons.

The image shows a normal brain slice and a brain slice of with severe AD.

Featured Genetics Open Neuroscience Articles

·November 14, 2013·4 min read

Understanding a Protein’s Role in Familial Alzheimer’s Disease

Researchers use a novel genomic approach to better understand genetic mutations associated with familial Alzheimer's disease.

Featured Genetics

·November 14, 2013·4 min read

FDA Approved Immune-Modulating Drug Unexpectedly Benefits Mice With Fatal Mitochondrial Defect

Rapamycin, a transplant anti-rejection drug, enhances survival and reduces the disease progression in a mouse model of Leigh's syndrome, a new study reports.

The image shows microtubule disintegration in alzheimer's disease.

Featured Neurology

·November 13, 2013·2 min read

High Blood Pressure in Middle Age Versus Old Age May Better Predict Memory Loss

According to a new study, middle aged people with high pulse pressure are more likely to have biomarkers for Alzheimer's disease in their spinal fluid than those with lower pulse pressure.

The illustration shows a cut away to the brain areas associated with Alzheimer's disease.

Featured Psychology

·November 12, 2013·4 min read

New Research May Improve Early Detection of Dementia

Analyzing scores obtained from cognitive tests, researchers believe they have developed a model which could detect early signs of dementia.

Featured Neurology

·November 11, 2013·2 min read

Symptoms of Parkinson’s Disease Linked to Fungus

Researchers have discovered a volatile organic compound, 1-octen-3-ol, which is often emitted by mold, could be linked to the symptoms of Parkinson's disease.

The illustration shows parvalbumin-expressing interneurons delivering chemical messages to neurons.

Featured Neuroscience

·November 11, 2013·3 min read

Signal Found to Enhance Survival of New Brain Cells

Researchers discover how parvalbumin-expressing interneurons, which usually limits stem cell activity, can also encourage the survival of the stem cells' progeny.

These graphs compare predictions made with the L-GoM (used to validate the model for predicting time to Alzheimer’s disease endpoints) with the actual outcomes.

Featured Neurology

·November 7, 2013·5 min read

New Method Predicts Time from Alzheimer’s Onset to Nursing Home and Death

Researchers have clinically validated a new method to predict the time it takes to enter full-time care in nursing homes or death for patients with Alzheimer's disease.