Schwann cells are much more prolific in generating myelin than previously believed. Knocking out the fbxw7 gene in mouse models, researchers discovered individual Schwann cells began to spread myelin across many axons.
Cannabidiol may be able to bypass the blood-brain barrier to effectively deliver medications directly to the brain.
In response to injury, microglia cross the spinal boundary from the central nervous system to the peripheral nervous system. While in the PNS, microglia provide the function of clearing cellular debris at the point of injury, then return to the CNS in an altered state. Researchers propose this could account for some damage associated with neurodegenerative diseases.
By optimizing neurons with CRISPR gene editing technology, researchers will have new ways to study genetic influences on brain health and disease, a new study reports.
Studying animal models, researchers have identified previously unknown types of immune cells that are present in the brains of those with multiple sclerosis.
Researchers have developed a novel 3D printed scaffolding that mimics natural anatomy and boost stem cell treatment for spinal cord repair. While the initial scaffolds have been designed for rat models of SCI, researchers report the approach is scalable to humans.
A new study reveals the intestine as a source of immune cells that help reduce neuroinflammation in patients with multiple sclerosis. Increasing the number of these cells helps block inflammation entirely, researchers report.
Researchers report oligodendrocytes may be critical to the remyelination process.
Researchers say improving the function of lymphatic vessels can dramatically enhance memory and learning ability in aging mice.
Researchers have successfully used stem cell therapy to regenerate neurons in damaged areas of zebra fish spinal cords. The treatment helped to restore movement following SCI. The findings raise the possibility of developing new treatments for humans suffering paralysis as a result of spinal cord injury.
Weight bearing leg exercises send signals to the brain which are vital for the production of healthy neural cells, researchers report.