A new study explores the potential link between the gut microbiome and mental health. Researchers report depression may be influenced by disturbances to gut bacteria, suggesting nutrition and diet, in combination with other strategies, could help treat the disorder.
Researchers have identified a unique biomarker in the blood of people with Multiple Sclerosis. Using a simple blood test, researchers were able to identify those with MS and discriminate between people at different stages of the disease.
Researchers report oligodendrocytes may be critical to the remyelination process.
Hyaluronic acid, a substance naturally produced by the human body and a popular additive in cosmetics that boast plumper skin, may be a useful tool in treating neuroinflammation.
Magnetic microrobots move against fluid flow and precisely deliver substances to neural materials.
A gene mutation which causes Lesch-Nyhan syndrome could provide clues to the developmental and neurological defects noted in other neurodegenerative diseases.
CRISPR gene editing created the G795A amino acid which was introduced to microglia derived from human stem cells. Researchers were able to transplant the donor microglia immune cells into humanized rodent models while administering an FDA-approved cancer drug called pexidartinib. The inclusion of the amino acid cause the donated microglia to thrive and resist the drug, while the host microglia died. The findings open the door for new methods of using microglia to treat a range of neurodegenerative disorders.
Researchers say their findings about immune system changes early in Alzheimer's could lead to new blood tests that may be used to detect the disease before it becomes symptomatic.