Researchers discover how a neurotoxin commonly used for cosmetic procedures can travel into the CNS.
A healthy and diverse microbiome is essential for quickly clearing viral infections in the nervous system to prevent risks associated with multiple sclerosis. Mice with lower gut bacteria had weaker immune responses and were unable to eliminate viruses, leading to worsening paralysis. Those treated with antibiotics before infection had fewer microglia.
Researchers have developed a novel 3D printed scaffolding that mimics natural anatomy and boost stem cell treatment for spinal cord repair. While the initial scaffolds have been designed for rat models of SCI, researchers report the approach is scalable to humans.
Researchers have devised techniques that allowed them to successfully replace dysfunctional microglia.
Researchers discover a link between neuroinflammation associated with impairment to the blood-brain barrier and intestinal permeability in people with ASD.
Using a mathematical model based on experimental data from multiple sclerosis patients, researchers performed computer simulations of the different known biological processes associated with the disease. They discovered the symptoms and disease course are produced by the same underlying mechanism that damages the nerve cells over time.
Researchers have identified structural 'footprints' that allow certain virus vectors reach the brain easily.
Researchers have successfully used stem cell therapy to regenerate neurons in damaged areas of zebra fish spinal cords. The treatment helped to restore movement following SCI. The findings raise the possibility of developing new treatments for humans suffering paralysis as a result of spinal cord injury.
Performing post-mortem staging of the brains and spinal cord tissue of patients with ALS, researchers discover the neurodegenerative disease could progress from one start point in the CNS to other regions of the brain and spinal cord.
Researchers say their findings about immune system changes early in Alzheimer's could lead to new blood tests that may be used to detect the disease before it becomes symptomatic.
Working with fruit flies, researchers identify a mechanism which helps explain how neurons which make up the visual system are generated.