Tufts researchers have developed neurotransmitter-lipid hybrids that help transport therapeutic drugs and gene editing proteins across the blood-brain barrier in mice.
Psychological symptoms, such as depression and anxiety, may be a sign COVID-19 is affecting the central nervous system of patients, a new study reports.
Chandelier cells have an unusual direct method of communication. Unlike other neurons, chandelier cells connect directly to the part of a target neuron that initiates a spike.
From losing the sense of taste or smell to developing an increased risk of stroke, researchers investigate both the known and potential long-term implications of COVID-19 infection in the brain.
Damage to the nasal epithelium increases the risk of bacteria entering into the brain, potentially resulting in long-term health problems.
Enhancing mitochondrial transportation and cellular energetics could help promote regeneration and function following spinal cord injury.
A global knockout of the thrombin receptor PAR1 accelerates myelin development. The findings could help with the development of treatments for diseases associated with demyelination, like multiple sclerosis.
Lewy body disorders, including Parkinson's disease and Lewy body dementia, comprise of two distinct subtypes. One subtype originates in the peripheral nervous system (PNS) of the gut and spreads to the brain. The other originates in the brain, or enters the brain via the olfactory system, before spreading to the brainstem and PNS.
People with functional dizziness do not appear to process sensory-motor impression correctly. Instead, they rely on a stored memory model which no longer matches immediate reality.
A healthy and diverse microbiome is essential for quickly clearing viral infections in the nervous system to prevent risks associated with multiple sclerosis. Mice with lower gut bacteria had weaker immune responses and were unable to eliminate viruses, leading to worsening paralysis. Those treated with antibiotics before infection had fewer microglia.
Hyaluronic acid, a substance naturally produced by the human body and a popular additive in cosmetics that boast plumper skin, may be a useful tool in treating neuroinflammation.
Severed axonal segments signal to Schwann cells to begin actin sphere formation and axon disintegration. If the process is disrupted, axon disintegration is slowed and axon fragments impair nerve regeneration.
