Researchers have discovered how synthetic molecules latch onto amyloid peptide fibrils. The discovery could help develop new therapies to halt Alzheimer’s disease.
Bexarotene, an anti-cancer drug which is about to be tested in a clinical trial as a potential treatment for Alzheimer’s disease, fails to reduce amyloid plagues; according to researchers replicating the original study.
According to new research, people who had skin cancer were almost 80% less likely to later develop Alzheimer’s disease.
Researchers have identified biomarkers for Alzheimer’s disease which accurately predict the development of the disease years prior to symptoms developing.
Researchers have found compelling evidence that older adults can eliminate forgetfulness and perform as well as younger adults on memory tests. The findings have intriguing implications for designing learning strategies for older adults.
Researchers combined genetic data with neuroimaging in order to identify genes associated with amyloid plaque deposits in Alzheimer’s disease patients. The study is believed to be the first genome-wide association study of plaque deposits using a specialized PET scan tracer that binds to amyloid.
A new study suggest that along with amyloid deposits, white matter hyperintensities may be a second necessary factor for the development of Alzheimer’s disease.
Researchers upend a long-held view about the basic functioning of a key receptor molecule involved in signaling between neurons. The study describes how a compound linked to Alzheimer’s disease impacts NMDA receptors and weakens synaptic connections between brain cells.
Researchers recently developed a system for observing real-time brain activity in a live mouse. The device could prove useful in studying new treatments for Alzheimer’s and other neurodegenerative diseases.
Researchers discover neuronal activity can stimulate tau release from healthy neurons in the absence of cell death. The study shows treatment of neurons with known biological signaling molecules increases the release of tau into the culture medium.