cogntive decline

New Research Determines How a Single Brain Trauma May Lead to Alzheimer’s Disease

A study, performed in mice and utilizing post-mortem samples of brains from patients with Alzheimer’s disease, found that a single event of a moderate-to-severe traumatic brain injury (TBI) can disrupt proteins that regulate an enzyme associated with Alzheimer’s. The paper, published in The Journal of Neuroscience, identifies the complex mechanisms that result in a rapid and robust post-injury elevation of the enzyme, BACE1, in the brain. These results may lead to the development of a drug treatment that targets this mechanism to slow the progression of Alzheimer’s disease.... Read More...

Synthetic Stimulants Called Bath Salts Act in the Brain Like Cocaine

Results of a new study offer compelling evidence for the first time that mephedrone, like cocaine, does have potential for abuse and addiction. “The effects of mephedrone on the brain’s reward circuits are comparable to similar doses of cocaine,” Dr. Malanga, a professor of neurology, pediatrics and psychology at UNC School of Medicine said. “As expected our research shows that mephedrone likely has significant abuse liability.”... Read More...