FeaturedNeurologyNeurosciencePainPsychology·May 21, 2019·2 min readMultiple brain regions moderate and link depressive mood and painPeople with higher levels of depressive moods exhibited heightened sensitivity to pain, and had greater activation in the prefrontal cortex, insula and somatosensory cortex.Read More
FeaturedNeurologyNeurosciencePain·May 16, 2019·2 min readThe insular cortex processes, and drives learning from painUsing optogenetics to 'switch off' the insular cortex in mice experiencing a painful event resulted in a less fearful reaction to pain. The ability of the mice to learn avoidance from the pain event was also reduced.Read More
FeaturedNeurologyNeurosciencePain·May 14, 2019·4 min readCommon antibiotic may increase nerve damage and peripheral neuropathy riskFluoroquinolone antibiotics, such as Levofloxacin and Ciprofloxacin, appear to increase the risk of peripheral neuropathy by 47%. However, there is no significant increased risk of developing neuropathy associated with amoxicillin use.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience ArticlesPain·May 7, 2019·4 min readDoes insulin resistance cause fibromyalgia?Study finds a pathogenic relationship between insulin resistance and fibromyalgia. Treating fibromyalgia with metformin, a drug that combats insulin resistance, resulted in a dramatic reduction of pain levels for patients.Read More
FeaturedNeurologyNeurosciencePain·April 29, 2019·4 min readNewfound autoimmune syndrome causes muscle pain, weaknessResearchers have identified a new autoimmune disease that causes muscle pain and weakness. Large-histiocyte-related immune myopathy (LHIM), generates similar results to the condition rhabdomyolysis in blood chemistry samples. LHIM can effectively be treated with anti-inflammatory drugs to help reduce symptoms.Read More
FeaturedGeneticsNeurologyPain·April 8, 2019·5 min readMigraine-linked protein exhibits sex-specific pain effectsCGRP, a protein associated with migraine pain, appears to act differently between sexes. Researchers say a female-specific mechanism of downstream CGRP receptor activation is likely to contribute to the higher prevalence of migraine in women.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience ArticlesPain·March 31, 2019·5 min readPairing music with medication offers potential therapeutic strategy to manage painClassical music exposure paired with ibuprofen reduced response to inflammation pain by 93%, compared to exposure to the medication alone in mouse models of pain. For those exposed to just music, researchers report a 77% reduction in surgical pain.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience ArticlesPain·March 29, 2019·5 min readWoman with novel gene mutation lives almost pain-freeA rare genetic mutation has been associated with pain insensitivity. The findings could further research into new treatments to target pain.Read More
FeaturedNeurologyNeurosciencePain·March 13, 2019·5 min readBlunting pain’s emotional componentBlocking the release of dynorphin, researchers restore motivation in animals experiencing pain. The findings may help in the development of new, less addictive, pain medications.Read More
FeaturedNeurosciencePain·March 12, 2019·3 min readNeuroscientists Find Brain Pathway Supporting an Intersection of Taste and PainResearchers have identified a pathway near the midbrain where neural messages for taste and pain converge, a new study reports.Read More
FeaturedNeurologyOpen Neuroscience ArticlesPain·February 13, 2019·7 min readBreakthrough in Developing Blood Test for PainResearchers have identified biomarkers in the blood which can help determine the severity of a person's pain level. The findings could help doctors to accurately measure pain and stem the opioid crisis.Read More
FeaturedNeurologyNeurosciencePain·January 28, 2019·4 min readSleep Loss Heightens Pain Sensitivity and Dulls Brain’s Painkilling ResponseResearchers report sleep deprivation intensifies and prolongs pain.Read More