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Pain

Pain Neuroscience news articles cover science research about pain receptors, nociceptors, nociception, sensory neurons, somatosensory cortex, chronic pain, acute pain, nocioceptors, musculoskeletal pain, therapies, phantom limb pain and other pain research.

Featured Genetics Neurology Neuroscience Pain

·June 1, 2026·8 min read

HIV Protein gp120 Directly Amplifies Spinal Pain Receptors

A new study isolates the exact molecular mechanisms by which the viral protein glycoprotein 120 (gp120) intensifies neuropathic suffering.

Featured Neurology Neuroscience Pain

·May 26, 2026·8 min read

Brain Pathway Identified That Amplifies Nocebo Pain Responses

Summary: Researchers mapped the precise brain pathway that drives the nocebo effect, the biological phenomenon where negative expectations actively amplify...

Featured Neurology Neuroscience Pain

·May 22, 2026·8 min read

Psilocybin Resets Brain Pain Networks and Boosts Painkillers

A single dose of psilocybin provides up to a month of nerve pain relief and fundamentally supercharges the efficacy of traditional painkillers.

Featured Neurology Neuroscience Pain

·May 19, 2026·11 min read

Tracking Facial Micromovements to Measure Pain

A new study demonstrates that tracking high-speed facial micromovement spikes provides an objective, quantifiable metric for human discomfort.

This shows an older woman surrounded by leaves.

Featured Neuroscience Pain Psychology

·May 8, 2026·9 min read

The “Goldilocks” Choice: Why Older Adults are Turning to Cannabis

New research shows that seniors are turning to edible cannabis to manage pain and sleep, often choosing "Goldilocks" combination products based on advice from friends rather than doctors.

Featured Neuroscience Pain

·April 23, 2026·7 min read

25% of Chronic Pain Patients Show ADHD Traits

A study of 1,000 Japanese patients reveals that undiagnosed ADHD traits may be a hidden driver behind treatment-resistant chronic pain.

Featured Neurology Neuroscience Pain

·April 16, 2026·8 min read

The Brain Circuitry of Placebo Pain Relief

Researchers have pinpointed the brain's "placebo circuit." By training the brain to release its own endorphins in the vlPAG region, they achieved broad-spectrum pain relief without the need for addictive drugs.

Featured Neurology Neuroscience Pain

·April 2, 2026·9 min read

Brain Circuit That “Invents” Chronic Pain Identified

Neuroscientists have identified a dedicated brain circuit responsible for chronic pain. By silencing this loop, researchers were able to end pain hypersensitivity in mice without affecting their ability to feel necessary, acute pain.

Featured Neurology Neuroscience Pain

·April 1, 2026·9 min read

High-Potency Opioid Relieves Pain Without the Risks

Researchers have engineered a novel nitazene-based opioid, DFNZ, that provides potent pain relief without causing respiratory depression or addiction. The "superagonist" drug could revolutionize treatment for chronic pain and opioid use disorder.

This shows a person's face surrounded by ice.

Featured Neurology Neuroscience Pain

·March 25, 2026·9 min read

Tiny Fat Molecule Triggers the Sensation of Cold

Scientists have mapped the atomic movement of TRPM8, the protein that senses cold and menthol. This "molecular movie" reveals how lipids lock the protein open, providing a new target for treating cold-induced pain.

This shows a person holding their head in pain.

Featured Neurology Neuroscience Pain Psychology

·March 19, 2026·9 min read

Why Chronic Pain Leads to Depression

New research reveals that the hippocampus acts as a control center for chronic pain, and a specific "inflammatory switch" determines who develops depression.