Brain CancerFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·May 16, 2019·4 min readMutations Synergize in Pediatric Brain CancerThe epigenetic histone mutation H3.1K27M works in combination with ACVR1 mutations to cause diffuse intrinsic pontine glioma tumors to form and grow quickly.Read More
Brain CancerFeaturedNeurologyNeuroscience·May 10, 2019·4 min readNew brain tumor imaging technique uses protein found in scorpion venomA synthetic, non-toxic form of scorpion venom helps illuminate brain tumors when stimulated by a near-infrared laser. A clinical trial of the agent showed it to be safe for use in brain cancer patients.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·April 30, 2019·3 min readNew technique may improve detection and treatment of advanced brain cancerResearchers discovered changes in thousands of genes induced by the tumor microenvironment. The study may help in identifying new biomarkers for the early detection, and subsequent treatment, of brain cancers.Read More
Brain CancerFeaturedGeneticsNeuroscienceOpen Neuroscience Articles·April 16, 2019·4 min readScientists ‘reverse engineer’ brain cancer cells to find new targets for treatmentUsing CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·April 11, 2019·4 min readShutting down deadly pediatric brain cancer at its earliest momentsDysregulation of Zfp36l1 causes neural lineage progenitor cells to grow rapidly, taking on the properties of fast growing stem cells as they become cancerous.Read More
Brain CancerFeaturedNeurologyNeuroscience·April 6, 2019·4 min readNew hope for treating childhood brain cancerDIPG cancer cells exposed to MI-2 fail to maintain healthy levels of cholesterol and die quickly, by inhibiting lanosterol synthase. Additionally, while MI-2 destroys glioma cancer cells, the drug does not damage healthy brain cells.Read More
Brain CancerFeaturedNeurologyNeuroscience·March 31, 2019·4 min readNew glioblastoma vaccine shows promising results in phase Ib clinical trialA new vaccine for glioblastoma brain cancer suspends tumor growth and is well tolerated by patients, according to the results of an early phase clinical trial.Read More
Brain CancerFeaturedNeurologyNeuroscience·March 22, 2019·4 min readNew drug combination shows promise for common pediatric brain tumorCombining carboplatin, a common chemotherapy drug, with everolimus, a drug that blocks mTOR, is effective at inducing apoptosis and slowing tumor growth in patients with pediatric low-grade glioma brain cancer.Read More
Brain CancerFeaturedNeurologyNeuroscience·March 6, 2019·5 min readRadiation After Surgery Triples Survival for Ependymoma, a Type of Pediatric Brain TumorA study shows that postoperative radiation improves outcomes for children with ependymoma, even those with historically poor prognoses and the very young.Read More
Brain CancerFeaturedNeuroscienceOpen Neuroscience Articles·February 20, 2019·3 min readNew AI Can Identify and Predict Development of Cancer Symptom ClustersA newly developed AI is able to identify and predict the development of a combination of symptoms associated with chemotherapy.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·February 11, 2019·5 min readImmunotherapy Can Be Effective in Treating People with Recurrent GlioblastomaResearchers report administering immunotherapy treatment prior to surgery for those with recurring glioblastoma brain cancer is more effective that using the treatment after surgery.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·January 25, 2019·4 min readThe Hitchhiker’s Guide to Defeating GlioblastomaResearchers have developed a new approach that uses microRNA in combination with chemotherapy to help treat glioblastoma brain cancer. In preclinical models, the approach increases survival of the deadly brain cancer five fold.Read More
