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regenerative medicine

The image shows pencil drawings of sea lampreys by Alexander Francis Lydon.

·February 25, 2013·3 min read

Scientists Find Genes Linked to Human Neurological Disorders in Sea Lamprey Genome

Scientists have identified several genes linked to human neurological disorders, such as Alzheimer’s disease, Parkinson’s disease and spinal cord injury, in the sea lamprey. The lamprey has large, identified neurons in its brain and spinal cord, making it an excellent model to study regeneration at the single cell-level.

The image shows lead researcher Paolo Macciarini performing surgery.

Featured Genetics

·February 18, 2013·2 min read

Stem Cell Based Bioartificial Tissues and Organs

Known for successfully transplanting a bioengineered stem cell-based trachea, surgeon Paolo Macchiarini plans to use his technique to recreate more complex tissue. He has recently made attempts to regenerate brain tissue in rats and mice.

The image shows a person undergoing a deep brain stimulation implant surgery.

Featured Neurology

·February 12, 2013·4 min read

In Some Dystonia Cases, Deep Brain Therapy Benefits may Linger After Device is Turned Off

According to a new report, two patients with Dystonia were freed from the severe debilitating effects of the disease through deep brain stimulation therapy, continued to have symptom relief for months after their devices accidentally were fully or partly turned off.

The image shows a coronal MRI scan of a patient with ALS.

Featured Neurology

·February 12, 2013·3 min read

Novel Protein May Help Detect Lou Gehrig’s Disease and Dementia

Researchers discover an abnormal protein that accumulates in the brains of patients affected with ALS and frontotemporal dementia. The findings have uncovered a potentially new therapeutic target and biomarker that would allow clinicians to confirm diagnosis of the diseases.

The image shows a capillary regeneration model. The caption best describes the image.

Featured Neuroscience

·February 11, 2013·4 min read

Simulations Show how Blood Vessels Regroup after Stroke

By simulating patterns of microvasculature cell growth and compare the results with real networks grown in lab, researchers hope to direct how they grow into the tiny blood vessels that feed the brain and help people regain functions lost to stroke and disease.

The image shows Jacob with a female researcher.

Featured Genetics

·February 7, 2013·5 min read

Experimental Gene Therapy Treatment for Duchenne Muscular Dystrophy offers Hope for Youngster

A nationwide clinical trial for a new type treatment that could offer help to those suffering from Duchenne Muscular Dystrophy, a devastating neuromuscular disease.

The image shows an over-sized terminal forms a synapse with a dendritic spine. The caption best describes the image.

Featured Neurology

·February 7, 2013·3 min read

Excess Protein Linked to Development of Parkinson’s Disease

Researchers suggest the overexpression of a protein called alpha-synuclein appears to disrupt vital recycling processes in neurons. The study may have major implications for more fully understanding the causes and mechanisms of Parkinson’s disease.

The image shows the structure of protein LRRK2.

Featured Genetics

·February 6, 2013·4 min read

Study Points to Possible Cause and Treatment for Non-familial Parkinson’s

Researchers identify a protein trafficking defect within brain cells that may underlie common non-familial forms of Parkinson’s disease. The study implicates two genetic variants that disrupt protein sorting in neurons.

Image shows brain slices with deposits of proteins associated with Alzheimer's and Parkinson's disease.

Featured Neurology

·February 5, 2013·3 min read

Study Confirms No Transmission of Alzheimer’s Proteins Between Humans

While evidence suggests pathological proteins linked to the onset and progression of neurodegenerative disorders are capable of spreading from cell-to-cell within the brains of affected individuals, new research shows no evidence to support concerns that these abnormal disease proteins are “infectious” or transmitted from animals to humans or from one person to another.

The image shows amyloid plaques in a mouse's hippocampus. The caption best explains the image.

Featured Neurology

·February 5, 2013·5 min read

Damaged Blood Vessels Loaded with Amyloid Worsen Cognitive Impairment in Alzheimer’s Disease

Researchers have discovered that amyloid peptides are harmful to the blood vessels that supply the brain with blood in Alzheimer's disease, thus accelerating cognitive decline by limiting oxygen-rich blood and nutrients.

A man is standing with the help of a walker in front of a tower of electronics as a woman sits nearby.

Electrophysiology Featured Neurology

·February 5, 2013·5 min read

Reflex Control Could Improve Walking After Incomplete Spinal Injuries

A training regimen to adjust the body's motor reflexes may help improve mobility for some people with incomplete spinal cord injuries. During training, the participants were instructed to suppress a knee jerk-like reflex elicited by a small shock to the leg. Those able to calm hyperactive reflexes saw improvements in their walking.

The image shows multi-colored jigsaw pieces around a dictionary definition of autism.

Autism Featured

·February 4, 2013·3 min read

Children with Autism at Significant Risk for Feeding Problems and Nutritional Deficits

A comprehensive analysis of feeding behavior in children with autism spectrum disorders indicates that these children are five times more likely to have a feeding problem, including extreme tantrums during meals, severe food selectivity and ritualistic mealtime behaviors.

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regenerative medicine

Scientists Find Genes Linked to Human Neurological Disorders in Sea Lamprey Genome

Stem Cell Based Bioartificial Tissues and Organs

In Some Dystonia Cases, Deep Brain Therapy Benefits may Linger After Device is Turned Off

Novel Protein May Help Detect Lou Gehrig’s Disease and Dementia

Simulations Show how Blood Vessels Regroup after Stroke

Experimental Gene Therapy Treatment for Duchenne Muscular Dystrophy offers Hope for Youngster

Excess Protein Linked to Development of Parkinson’s Disease

Study Points to Possible Cause and Treatment for Non-familial Parkinson’s

Study Confirms No Transmission of Alzheimer’s Proteins Between Humans

Damaged Blood Vessels Loaded with Amyloid Worsen Cognitive Impairment in Alzheimer’s Disease

Reflex Control Could Improve Walking After Incomplete Spinal Injuries

Children with Autism at Significant Risk for Feeding Problems and Nutritional Deficits

Hippocampus Predicts Rewards by Reorganizing Memories

Memory Rewritten: Study Finds No Clear Line Between Episodic and Semantic Retrieval

Brain Stimulation Method Can Evaluate Consciousness in Alzheimer’s Disease

Early Intervention Helps Most Autistic Children Acquire Spoken Language

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