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Parkinson’s disease

Featured Genetics Neurology

·September 11, 2020·5 min read

New Points of Attack Against Parkinson’s Disease

Study suggests an alternative strategy for restoring cellular abnormalities in in-vitro models of Parkinson's disease.

Featured Neurology

·September 2, 2020·6 min read

Common Drugs Tied to Increased Risk of Cognitive Decline

Anticholinergic medications, commonly used for conditions including allergies, high blood pressure, Parkinson's disease, and motion sickness, have been linked to an increased risk of cognitive decline and memory problems, especially in those with genetic risk factors for Alzheimer's disease.

Featured Neurology Neuroscience Open Neuroscience Articles

·August 31, 2020·3 min read

Neurons Protect Themselves From Degeneration by Adapting Their Metabolism

Neurons can counteract degeneration and promote survival by adapting their metabolism.

Featured Genetics Neurology Open Neuroscience Articles

·August 23, 2020·4 min read

Unique Protein Structures Could Hold the Key to Parkinson’s Disease

Researchers have discovered a series of misfolded alpha-synuclein protein structures never previously observed. The alpha-synuclein fibers were larger than previously reported and adopted a striking variety of shapes. The work lays the foundation for a detailed analysis of misfolded alpha-synuclein structures and could provide a better understanding of the neurobiology of Parkinson's disease.

Featured Neurology

·August 19, 2020·5 min read

Can a Healthy Diet Reduce Risk of Parkinson’s?

Eating a diet rich in vegetables and nuts during middle age is linked to fewer symptoms that may precede Parkinson's disease.

Featured Genetics Neurology

·June 24, 2020·6 min read

One-time treatment generates new neurons and eliminates Parkinson’s disease

Researchers administered PTB antisense oligonucleotide treatment directly to the midbrain of mice. In the mouse models exposed to the treatment, a small subset of astrocytes converted to neurons, increasing the number of neurons by 30%. Three months after treatment, mice were completely free of Parkinson's disease symptoms and remained in remission for the rest of their lives.

Featured Neurology

·June 15, 2020·7 min read

Disrupted circadian rhythms linked to later Parkinson’s diagnoses

Circadian rhythm disruptions in older men have been linked to an increased risk of developing Parkinson's disease. The findings suggest circadian disruptions may reflect the neurodegenerative processes already affecting the brain's internal clock prior to the diagnosis of Parkinson's. Circadian disruptions, researchers say, could be considered an early warning sign of Parkinson's.

Featured Neurology Neuroscience

·May 20, 2020·4 min read

Link between diesel exhaust and risk of Parkinson’s discovered

Researchers have uncovered the process by which air pollution can damage brain cells, leading to an increased risk of Parkinson's disease. Chemicals found in diesel fuel reduced autophagic flux, which is a major pathway implicated in neurodegeneration.

This shows different d2rs in the striatum

Featured Neurology Neuroscience Open Neuroscience Articles

·May 13, 2020·3 min read

Significant differences exist among neurons expressing dopamine receptors

Dopamine receptors have different molecular features and functions depending on their anatomical location within the striatum. The findings could help develop better-targeted treatments for a range of disorders from schizophrenia to Parkinson's disease.

This shows a person holding a cup of wateri

Featured Genetics Neurology Neuroscience

·May 1, 2020·5 min read

Parkinson’s dyskinesia mechanism explained

Involuntary movements and tremors caused as a result of taking dopamine replacement medications for Parkinson's disease can be alleviated through the suppression of RasGRP1.

Featured Neurology Neuroscience Open Neuroscience Articles

·April 30, 2020·3 min read

Researchers unravel protein mystery of three brain diseases

Researchers have identified two different shapes of alpha-synuclein associated with multiple systems atrophy (MSA) and Lewy body dementia. The structure of the protein is helical in MSA, causing the symptoms to occur more quickly and aggressively. In Lewy body dementia, the protein takes on a cylindrical form.

Featured Genetics Neurology Neuroscience

·April 27, 2020·3 min read

More evidence Parkinson’s disease may start in the gut

Enteric neurons appear to play a key role in the development of Parkinson's disease. The findings support the hypothesis and previous studies that the neurodegenerative disease may start in the gut before spreading to the brain. Researchers also found oligodendrocytes were affected during the early stages of Parkinson's, even before the loss of dopaminergic neurons.

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Parkinson’s disease

New Points of Attack Against Parkinson’s Disease

Common Drugs Tied to Increased Risk of Cognitive Decline

Neurons Protect Themselves From Degeneration by Adapting Their Metabolism

Unique Protein Structures Could Hold the Key to Parkinson’s Disease

Can a Healthy Diet Reduce Risk of Parkinson’s?

One-time treatment generates new neurons and eliminates Parkinson’s disease

Disrupted circadian rhythms linked to later Parkinson’s diagnoses

Link between diesel exhaust and risk of Parkinson’s discovered

Significant differences exist among neurons expressing dopamine receptors

Parkinson’s dyskinesia mechanism explained

Researchers unravel protein mystery of three brain diseases

More evidence Parkinson’s disease may start in the gut

Hearing Aids Linked to 23% Lower Dementia Risk in Epilepsy

Reading Is the Ultimate Cognitive Enhancer

Dual Brain-Machine Interfaces Unlock Bionic Hand Kinesthesia

Overcoming Endothelial Sorting to Cure Glioblastoma

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