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          Huntington’s disease

          This is an image of a striatal neuron with activated Dendra2 protein.
          FeaturedNeurology
          ·July 21, 2013·5 min read

          For a Healthy Brain, Don’t Let the Trash Pile Up

          A new study indicates that quickly clearing away defective proteins in the brain could help prevent some neurodegenerative disorders.
          Read More
          The illustration is a brain slice with advanced stage alzheimer's.
          FeaturedNeurologyNeuroscience Videos
          ·June 28, 2013·5 min read

          Scientists View ‘Protein Origami’ to Help Understand, Prevent Certain Diseases

          Using sophisticated imaging techniques, researchers observe a molecular protein folding process which could help better understand and treat neurodegenerative diseases and cancers.
          Read More
          The image shows the location of the nucleus accumbens in the brain.
          FeaturedNeuroscience
          ·June 7, 2013·4 min read

          Researchers Focus on a Brain Protein and an Antibiotic to Block Cocaine Craving

          A new study shows that the GLT1 protein plays a critical role in the craving for cocaine which develops after only a few days of cocaine use. However, exposure to ceftriaxone, an antibiotic used to treat meningitis, decreases cocaine cravings.
          Read More
          Images shows new medium spiny neurons (in green) integrating into brain's existing networks
          FeaturedGenetics
          ·June 6, 2013·5 min read

          Scientists Coax Brain to Regenerate Cells Lost in Huntington’s Disease

          Researchers mobilize the brain's native stem cells to replenish medium spiny neurons which are lost in Huntington's disease.
          Read More
          The image shows defective protein cells. The caption best describes the image.
          FeaturedGenetics
          ·February 26, 2013·5 min read

          Researchers Find Controlling Element of Huntington’s Disease

          Researchers discover a three molecule complex could be a target for treating Huntington's Disease, a genetic and currently incurable brain disease which causes movement disorders and dementia.
          Read More
          Brain image with the basal ganglia and other brain areas.
          FeaturedNeuroscience
          ·January 30, 2013·2 min read

          NIH Study Advances Understanding of Movement Control

          Voluntary movements involve the coordinated activation of two brain pathways that connect parts of deep brain structures called the basal ganglia, according to a study in mice.
          Read More
          Genetics
          ·September 18, 2012·1 min read

          New Findings on Protein Misfolding

          Researchers identified 21 proteins that specifically bind to a protein called ataxin-1. Twelve of these proteins enhance the misfolding of ataxin-1 and thus promote the formation of harmful protein aggregate structures, whereas nine of them prevent the misfolding.
          Read More
          FeaturedNeurology
          ·September 17, 2012·3 min read

          Toxic Protein Build-up in Blood Shines Light on Fatal Brain Disease

          A new light-based technique for measuring levels of the toxic protein that causes Huntington's disease (HD) has been used to demonstrate that the protein builds up gradually in blood cells.
          Read More
          FeaturedGeneticsNeurology
          ·July 11, 2012·3 min read

          Two Proteins Offer a Clearer Way to Treat Huntington’s Disease

          HD mice crossbred with mice that produced greater levels of PGC-1alpha showed dramatic improvement. Production of misfolded proteins was essentially eliminated and the mice behaved normally. “Degeneration of brain cells is prevented. Neurons don’t die,” said La Spada.
          Read More
          FeaturedGeneticsNeurology
          ·June 28, 2012·3 min read

          Human Model of Huntington’s Disease Created from Skin’s Stem Cells

          ‘HD in a dish’ will facilitate search for elusive treatment. An international consortium of Huntington’s disease experts, including several from...
          Read More
          FeaturedNeurologyNeuroscience Videos
          ·June 27, 2012·3 min read

          Nerve Pathway for Combating Axon Injury and Stress May Hold Benefits for Individuals With Neurodegenerative Disorders

          Researchers from the Huck Institutes’ Center for Cellular Dynamics, led by Center director Melissa Rolls, have found that a neuroprotective...
          Read More
          Brain CancerFeaturedGeneticsNeurologyNeuroscience
          ·June 20, 2012·3 min read

          Proposed Drug May Reverse Huntington’s Disease Symptoms

          Single treatment produces long-term improvement in animal models. With a single drug treatment, researchers at the Ludwig Institute for Cancer...
          Read More
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          This shows an anthrobot.

          Anthrobots: Tiny Biobots From Human Cells Heal Neurons

          This shows the outline of a person.

          RNA’s Pivotal Role in Fear Memory and PTSD Treatment

          This shows AI representations of bacterria.

          Lactobacillus Bacteria May Guard Against Anxiety and Depression

          This shows a fish.

          Stickleback Fish Reveal Insights into Animal Decision-Making

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