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Huntington’s disease
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Huntington’s disease

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FeaturedNeurologyNeuroscience
·January 20, 2023·6 min read

How Huntington’s Disease Affects Different Neurons

Researchers have identified how two different populations of neurons in the striatum are affected differently in Huntington's disease. The neurodegeneration of one of these populations leads to motor defects while damage to the other population located in striosomes may account for mood disorders associated with the early stages of Huntington's.
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FeaturedGeneticsNeurologyNeuroscience
·December 12, 2022·4 min read

CRISPR Technology Improves Huntington’s Disease Symptoms in Models

Using CRISPR gene editing to directly target RNA, researchers eliminated toxic protein buildup associated with Huntington's disease while not disrupting other human genes.
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FeaturedNeurologyNeuroscience
·October 28, 2022·6 min read

Cellular Housekeeping Process Implicated in Huntington’s Disease

Study reveals how aging impairs autophagy and how enhancing autophagy can prevent cells from dying in Huntington's disease.
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This shows a neuron
FeaturedGeneticsNeurologyNeuroscience
·September 27, 2022·4 min read

Study Probes Huntington’s Disease Protein’s Function in Injured Neurons

The Huntington's disease protein huntingtin may have a role external to the neurodegenerative disease. Researchers say Huntingtin is involved in neural injury and regeneration.
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FeaturedNeurologyNeuroscience
·September 19, 2022·3 min read

Discovery of the Causes of Brain Dysfunction in Patients With Huntington’s Disease

Researchers discovered decreased function in a protein critical for synaptic function in those with Huntington's disease.
Read More
This shows a brain
FeaturedGeneticsNeurologyNeuroscience
·August 17, 2022·3 min read

Reprogramming Human Skin Cells Into Aged Neurons to Study Neurodegenerative Disorders

Converting skin cell samples into neurons helps researchers gain a better understanding of the mechanisms of Huntington's disease.
Read More
This shows a brain and red blood cells
FeaturedNeurologyNeuroscience
·February 15, 2022·7 min read

A New Atlas of Cells That Carry Blood to the Brain

Researchers have created a comprehensive atlas of cell types in the brain's cerebrovascular system.
Read More
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FeaturedGeneticsNeurologyNeuroscience
·November 29, 2021·5 min read

Why Some People Experience Early Onset Neurodegenerative Diseases

A new study sheds light on the genetic causes of a range of neurodegenerative disorders, including ALS, Parkinson's disease, and Huntington's disease, and determines factors that impact the age of onset as well as disease severity.
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This shows a cluster of cells
FeaturedNeurologyNeuroscience
·October 5, 2021·4 min read

Study Detects Origins of Huntington’s Disease in Two-Week-Old Human Embryos

Synthesizing a human embryo from stem cells and using gene editing to insert the Huntingtin gene, researchers found the mutation affected the size of germ layers compared to the control embryos. Findings suggest Huntington's disease may be a neurodevelopmental disorder that presents as a neurodegenerative disease later
Read More
This shows a brain
FeaturedNeurologyNeuroscience
·July 15, 2021·4 min read

Autophagy May Be the Key to Finding Treatments for Early Huntington’s Disease

Disruption of autophagy may be at the root of the cognitive deficits experienced by those with Huntington's disease.
Read More
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FeaturedGeneticsNeurologyOpen Neuroscience Articles
·March 6, 2021·4 min read

Huntington’s Disease Driven by Slowed Protein-Building Machinery in Cells

The mutated huntingtin protein slows ribosome movement and decreases protein synthesis.
Read More
This is a graphic abstract from the study
FeaturedGeneticsNeurologyNeuroscience
·January 7, 2021·6 min read

Effects of Huntington’s Disease Mutation May Begin in Childhood

A new study adds to the growing body of evidence that the origin of Huntington's disease is rooted in childhood. Researchers say the HTT gene mutation affects both brain and body growth during development, and the increased susceptibility of brain cell death begins early in life.
Read More
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This shows the outline of a child and an adult's head

The More Traumatic the Childhood, the Angrier the Adult

This shows pills

Antidepressant Withdrawal Should Be Taken Seriously

This shows a person sweating

Odors From Other People’s Sweat Can Help Treat Social Anxiety

This shows the outline of a head

Spotting Early Signs of Dementia

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