Researchers shed light on what happens to specific neurons when neurodegenerative diseases impact movement. The findings could help in the development of new treatments for Parkinson's and Huntington's disease.
Gene expressions in the brain that occur early in development may explain why some cerebellar stem cell populations behave differently in people with SCA1, researchers report.
Researchers have developed a method to determine the length of mutated genes associated with Huntington's disease quickly and easily.
According to a new study, researchers have devised a new way to detect chemical damage to DNA that leads to genetic mutations which are responsible for an array of diseases, including ALS and other neurodegenerative diseases.
Researchers use a novel co-culturing method to create functional circuits that model Huntington's disease and find new clues to potential treatment approaches.
Researchers use an innovative new tool to observe protein aggregation throughout the life cycle of a worm.
Researchers work to understand how expanded polyglutamine tracts form the types of supramolecular structures that are presumed to be toxic to neurons.
Researchers have identified a novel type of cell death associated with Huntington's disease.
Mouse models of corticospinal injuries reveal adult neurons begin a natural regeneration process by reverting back to an embryonic state. The regeneration is sustained with the help of a gene more commonly associated with Huntington's disease.
Researchers discover the IP3R receptor can be locked into closed state by enzyme action. This could potentially play a role in the reduction of neuron signaling seen in some neurodegenerative disorders.
A new study adds to the growing body of evidence that the origin of Huntington's disease is rooted in childhood. Researchers say the HTT gene mutation affects both brain and body growth during development, and the increased susceptibility of brain cell death begins early in life.
According to a new study, the proteome undergoes extensive changes during aging.
