Latest

Huntington’s disease

·September 18, 2012·1 min read

New Findings on Protein Misfolding

Researchers identified 21 proteins that specifically bind to a protein called ataxin-1. Twelve of these proteins enhance the misfolding of ataxin-1 and thus promote the formation of harmful protein aggregate structures, whereas nine of them prevent the misfolding.

Featured Neurology

·September 17, 2012·3 min read

Toxic Protein Build-up in Blood Shines Light on Fatal Brain Disease

A new light-based technique for measuring levels of the toxic protein that causes Huntington's disease (HD) has been used to demonstrate that the protein builds up gradually in blood cells.

Featured Genetics Neurology

·July 11, 2012·3 min read

Two Proteins Offer a Clearer Way to Treat Huntington’s Disease

HD mice crossbred with mice that produced greater levels of PGC-1alpha showed dramatic improvement. Production of misfolded proteins was essentially eliminated and the mice behaved normally. “Degeneration of brain cells is prevented. Neurons don’t die,” said La Spada.

Featured Genetics Neurology

·June 28, 2012·3 min read

Human Model of Huntington’s Disease Created from Skin’s Stem Cells

‘HD in a dish’ will facilitate search for elusive treatment. An international consortium of Huntington’s disease experts, including several from...

Featured Neurology Neuroscience Videos

·June 27, 2012·3 min read

Nerve Pathway for Combating Axon Injury and Stress May Hold Benefits for Individuals With Neurodegenerative Disorders

Researchers from the Huck Institutes’ Center for Cellular Dynamics, led by Center director Melissa Rolls, have found that a neuroprotective...

Brain Cancer Featured Genetics Neurology Neuroscience

·June 20, 2012·3 min read

Proposed Drug May Reverse Huntington’s Disease Symptoms

Single treatment produces long-term improvement in animal models. With a single drug treatment, researchers at the Ludwig Institute for Cancer...

Featured Genetics Neurology

·June 7, 2012·3 min read

Researchers Identify Gene that Promotes Axon Destruction

Findings could have broad therapeutic potential for many neurodegenerative diseases. Degeneration of the axon and synapse, the slender projection through...

Neurology

·April 3, 2012·3 min read

Former Professional Baseball Pitcher Now Keeps His Strike Zone in Proteins

Perhaps no other biochemist in the world has his own baseball card, but University of Massachusetts Amherst doctoral student Elih...

Neuroscience

·March 30, 2012·3 min read

Biologists Identify a Key Enzyme Involved in Protecting Nerves From Degeneration

A new animal model of nerve injury has brought to light a critical role of an enzyme called Nmnat in...

Featured Neurology

·March 15, 2012·3 min read

Stem Cells Hint at Potential Treatment for Huntington’s Disease

Huntington’s disease, the debilitating congenital neurological disorder that progressively robs patients of muscle coordination and cognitive ability, is a condition...

Neurology

·June 24, 2011·2 min read