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hippocampus

·September 30, 2022·4 min read

Superager Brains Contain ‘Super Neurons’

Neurons in the memory-associated entorhinal cortex of super-agers are significantly larger than their cognitively average peers, those with MCI, and even in people up to 30 years younger. Additionally, these neurons contained no signs of Tau, a hallmark of Alzheimer's disease.

Featured Neurology Neuroscience

·September 29, 2022·4 min read

Metabolism Linked to Brain Health

Researchers have identified a link between metabolism and dementia-related brain measures. Obesity related to inflammation, kidney stress, or liver stress had the biggest impact on adverse brain health.

Featured Neuroscience

·September 28, 2022·3 min read

A Good Night’s Sleep Is a Tonic to Remember

Researchers reveal why a good night's sleep helps boost learning and memory.

Featured Neuroscience Psychology

·September 20, 2022·6 min read

Molecular Changes in the Brain in the Aftermath of a Traumatic Event May Help Explain Long-Term Susceptibility or Resilience

In mice genetically more susceptible to PTSD following a stressful event, researchers found an increased expression of cortisol receptors on neurons in the CA1 region of the dorsal hippocampus. Those increased receptors enabled an elevated expression of the HCN1 protein and TRIP8b, reducing neural excitability.

Featured Neuroscience Open Neuroscience Articles

·September 14, 2022·4 min read

A Switch Telling the Brain When to Learn and When to Remember

Study reveals a neural signal in the hippocampus that enables the brain to alternate between learning and remembering modes.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·September 9, 2022·5 min read

Jumping Gene Found to Be Strongly Linked to Depression, Fear, and Anxiety

The TOB gene plays a significant role in reducing depression, anxiety, and fear in mouse models. The findings could have positive implications for developing new treatments for disorders associated with psychiatric stress.

Featured Neuroscience

·August 25, 2022·3 min read

Potential Way to Tune the Brain Into Learning Mode

Study reveals how the element of surprise helps facilitate learning and memory retrieval.

Featured Neuroscience

·August 22, 2022·4 min read

Brains Cells Born Together Wire and Fire Together for Life

Neurons that were "born" at the same time show distinct connectivity and activity throughout the life of an animal.

Featured Neurology Neuroscience

·August 19, 2022·2 min read

Boosting Neuron Formation Restores Memory in Mice With Alzheimer’s Disease

Increasing neurogenesis by deleting the Bax gene in mouse models of Alzheimer's improved the animals' performance in tests measuring spatial recognition and contextual memory.

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Featured Neuroscience

·August 3, 2022·6 min read

The Brain Already Benefits From Moderate Physical Activity

Moderate physical activity was linked to increased volume in brain areas associated with memory, especially in older adults. Researchers say mild-to-moderate physical activity may have neuroprotective properties.

This shows a clock and a head made up of cog wheels

Featured Neuroscience

·August 2, 2022·3 min read

Neurons Sync Their Beats Like Clocks on the Wall

A group of hippocampal neurons show rhythmic activity at different frequencies in the desynchronized state, but can align their rhythmic frequency to produce a synchronized brain rhythm upon activation.

This shows glutamate on a hippocampal neuron

Electrophysiology Featured Neuroscience Open Neuroscience Articles

·July 27, 2022·2 min read

A Methodological Leap in the Exploration of Memory

Researchers have developed a comprehensive "toolbox" to establish that the mobility of receptors exists in intact brain tissue, and this mobility is critical for certain types of memory.