Studying rats in a virtual reality maze, researchers discover certain hippocampal neurons play a vital role in a specific mechanism of navigation.
A new study reveals how adipocytes, or fat cells, play a role in cognitive decline and increased neurodegeneration risks. Using genetically modified mouse models, researchers found oxidative stress through exposure to a Western diet increased the production of inflammatory cytokines confined to adipocytes and altered protein markers of memory and cognition in the hippocampus.
Scanning the brains of sleeping toddlers, researchers found the hippocampus is activated as memories for new words are formed. The findings suggest the hippocampus plays an important role in the formation of new word memories.
Serotonin-producing neurons in the brainstem release serotonin throughout the brain during moments of novel social encounters. The release of serotonin stimulates neurons in the medial septum via a subtype of serotonin-sensitive receptor molecules. Blocking the release of this receptor molecule prevents the formation of new social memories.
Mouse study identifies specific neurons and a signaling pathway to regions of the hindbrain that mediate sexual reproductive activity and physical activity that appear to influence activity behaviors during ovulation. The findings may provide valuable insights into how estrogen loss during menopause disrupts this activity.
The planar cell polarity (PCP) signaling pathway appears to play a significant role in the formation and maintenance of a large number of synapses.
Study shows chronic hyperglycemia impairs working memory performance and alters fundamental aspects of working memory brain networks. The findings strengthen the link between type 2 diabetes and Alzheimer's disease.
Preliminary new findings are raising concerns about the long-term effect of mild COVID-19 infection on neurological health and cognition.
Mouse study reveals chronic stress affects neurogenesis in the dentate gyrus.
Researchers identified specific receptors for acetylcholine that reroute information flow through memory circuits in the hippocampus. The findings could have implications for the development of drugs to help enhance or protect memory from diseases associated with cognitive decline.
Altered behaviors associated with LSD may be caused by a reduction in the normal communication between the hippocampus and visual cortex.