FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience ArticlesPain·March 29, 2019·5 min readWoman with novel gene mutation lives almost pain-freeA rare genetic mutation has been associated with pain insensitivity. The findings could further research into new treatments to target pain.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·March 29, 2019·5 min readResearchers discover two, rare genes associated with Alzheimer’s diseaseTwo rare genetic variants on the NOTCH3 and TREM2 genes have been identified in some Alzheimer's patients.Read More
FeaturedGeneticsNeuroscience·March 28, 2019·3 min readSingle Population of Stem Cells Contributes to Lifelong Hippocampal Neurogenesis: Mouse StudyThe findings support a continuous model of neurogenesis throughout development and adulthood.Read More
Brain CancerFeaturedNeurologyNeuroscience·March 22, 2019·4 min readNew drug combination shows promise for common pediatric brain tumorCombining carboplatin, a common chemotherapy drug, with everolimus, a drug that blocks mTOR, is effective at inducing apoptosis and slowing tumor growth in patients with pediatric low-grade glioma brain cancer.Read More
FeaturedNeuroscience·March 22, 2019·4 min readSleep and aging: Two sides of one coin?A link has been identified between oxidative stress, which has previously been linked to aging and neurodegeneration, and sleep. Oxidative stress activates neurons that control sleep function. The findings could help in the development of treatments for sleep disorders.Read More
FeaturedGeneticsNeurosciencePsychology·March 22, 2019·4 min readWhen neurons are out of shape, antidepressants may not workDifferences in serotonergic neuron morphology, along with altered gene expression have been identified in patients with MDD. The findings shed light on why some patients do not respond to SSRI antidepressants.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience ArticlesVisual Neuroscience·March 17, 2019·8 min readWith single gene insertion, blind mice regain sightGene therapy that targets retinal ganglion cells with light-sensitive cone opsins helps restore vision in mice. Researchers report a potential human treatment could be available within three years.Read More
FeaturedNeurologyNeuroscienceNeuroscience VideosOpen Neuroscience Articles·March 15, 2019·4 min readNew proof that narcolepsy is an autoimmune diseaseAutoreactive cytotoxic CD8 T cells have been detected in people with narcolepsy type one. The finding suggests levels of the T-cell reactivity, combined with specific gene expression, may spur on the development of NT1.Read More
FeaturedGeneticsNeuroscience·March 14, 2019·5 min readSerotonin Can Directly Regulate Gene Expression Inside Brain CellsSerotonin can chemically attach to histone proteins in the cell nucleus to help regulate gene expression. The findings may provide a better understanding of an array of psychological disorders and neurodegenerative diseases.Read More
FeaturedGeneticsPsychology·March 13, 2019·4 min readNIH-funded rodent study finds molecular link between adolescent alcohol use and adult anxietyAdolescent rats exposed to alcohol had a decrease of both Arc eRNA expression and Arc gene expression in the amygdala during adulthood. Additionally, the alcohol-exposed rats displayed increased anxiety behaviors as they aged.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·March 13, 2019·4 min readNew Cell Subtypes Classified in Mouse BrainA new process for classifying neurons in the brains of mice has been outlined by researchers from Cold Spring Harbor Laboratory. The platform pairs microscopy with genetic labeling at single neuron resolution, allowing researchers to reconstruct the brain, by providing information on every neuronal type's location.Read More
FeaturedGeneticsNeurosciencePsychology·March 12, 2019·5 min readScientists identify gene that keeps PTSD-like behavior at bay in female miceA new study reveals how a prion-like protein that is encoded by the TIA1 gene helps to regulate fear memories. TIA1, researchers report, may be a promising new target for the treatment of PTSD.Read More
