Latest

FMR1

·July 15, 2026·11 min read

Gene Therapy Reverses Severe Traits of Fragile X Syndrome

The therapy restored FMRP expression in crucial brain regions, resulting in reduced audiogenic seizure susceptibility, normalized sensory hyperactivity, and complete reversal of elevated low-gamma EEG power.

Autism Featured Genetics Open Neuroscience Articles

·April 4, 2023·5 min read

How an Autism Gene Contributes to Infertility

FMR1, a gene mutation that causes Fragile X syndrome is also implicated in premature ovarian failure, resulting in infertility in females. The mutation alters neurons that regulate reproduction in the brain and ovaries.

This shows a little girl playing with building blocks

Autism Featured Genetics Neuroscience

·December 13, 2021·5 min read

New Hope for People Living With a Genetic Cause of Autism

Gene editing may provide hope for the treatment of Fragile X, the leading genetic cause of autism.

Autism Featured Genetics Neuroscience

·December 16, 2020·3 min read

New Insights Into Fragile X Syndrome and the Fetal Brain

Researchers have identified a potential molecular mechanism that causes Fragile X syndrome in the developing fetal brain.

Featured Genetics Open Neuroscience Articles Psychology

·June 24, 2020·4 min read

Unexpected mental illnesses found in a spectrum of a rare genetic disorder

Fragile X syndrome patients with prematuration had a much earlier onset of neurological problems, including earlier symptoms of neurodegeneration. They also experienced emotional processing problems. Some of the most common emotional processing disorders reported were mood regulation, anxiety, and psychosis.

Autism Featured Genetics Open Neuroscience Articles

·December 3, 2018·3 min read

Genetic Background of Autism Connected to Stem Cell Dysfunction

Researchers report functional alterations in L-type calcium channels were detected in models of Fragile X syndrome.

Featured Neurology

·February 15, 2018·5 min read

Alzheimer’s Drug Repairs Brain Damage After Alcohol Binges: Rat Study

Researchers report a drug used to slow cognitive decline in Alzheimer's disease may help to reverse memory and learning problems in teens who binge drink.

Autism Featured Neuroscience

·January 18, 2018·4 min read

Fragile X Study Shows Normal Neurons That Interact Poorly

Researchers report neurons in mice with a genetic defect that causes Fragile X are similar to those in mice without the syndrome, but fail to interact correctly. This failure results in the cognitive impairment associated with FXS.

Featured Psychology

·August 23, 2017·4 min read

Children With Fragile X Syndrome Have a Bias Toward Threatening Emotion

A new study reports children with Fragile X syndrome show bias toward threatening rather than positive emotion.

Featured Genetics Neuroscience Open Neuroscience Articles

·August 9, 2017·4 min read

Insight into Learning via ‘Friend of Fragile X’ Gene

Researchers report FMR1 and ZC3H14 proteins both regulate mRNA, which may explain their importance in memory and learning.

Autism Featured Neuroscience Psychology

·May 15, 2017·4 min read

Diabetes Drug May Help With Symptoms of Fragile X

Researchers report a common diabetes drug helped to restore protein production in the brain to normal levels and repaired brain connections in mouse models of Fragile X.