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CRISPR

·March 31, 2020·3 min read

New insights into pain signaling in the brain

Study reveals how a neuropeptide called Big Dynorphin binds to the acid-sensing ion channel receptor, causing pain signals to be sent around the body.

Autism Featured Genetics Neuroscience

·January 29, 2020·5 min read

Link between autism and cognitive impairment discovered

Study identifies a short gene segment crucial for brain development and information processing. The absence of the gene segment induces altered social behaviors, learning difficulties, and memory deficits, which are hallmarks of a subset of ASD.

Auditory Neuroscience Featured Neuroscience Open Neuroscience Articles

·January 2, 2020·3 min read

Hearing develops in tandem with form and function

Findings may provide clues that may help researchers develop new techniques to regenerate hair cells in the inner ear and reverse hearing loss.

This shows a drawing of a fetus attached to a placenta

Featured Genetics Neuroscience

·December 27, 2019·3 min read

Placental protein makes a critical contribution to healthy fetal development

Study reveals how a protein that transports essential amino acids across the placenta plays a role in fetal development. Deficiencies of the SNAT4 protein may result in developmental abnormalities and a higher risk of miscarriage.

Featured Genetics Neuroscience

·November 21, 2019·5 min read

Simulations suggest embryo selection based on traits like height or IQ is still far off

The ability to select specific traits, such as height or IQ, brought about by multiple genes is more complicated than most people realize.

Featured Genetics Neuroscience Psychology

·September 23, 2019·4 min read

Gene regulators work together for oversized impact on schizophrenia risk

Using CRISPR to alter the expression of four schizophrenia implicated genes which harbor expression quantitative trait loci, researchers were able to mirror gene expression changes seen in postmortem brains of those suffering from three mental health disorders.

This shows cells from the clock in a dish

Featured Genetics Neuroscience Neuroscience Videos Open Neuroscience Articles

·August 29, 2019·4 min read

Human developmental clock mimicked in a dish

The human development 'clock in a dish' opens up new avenues for research and provides a way to replicate developmental disorders.

Featured Genetics Neuroscience

·June 12, 2019·7 min read

Using gene editing, neuroscientists develop a new model for autism

Using CRISPR gene editing, researchers introduce the SHANK3 gene variant into macaque monkeys. SHANK3 has previously been linked to autism in humans. The monkeys with the SHANK3 mutations exhibited behavioral traits and brain activity patterns similar to those seen in humans on the autism spectrum, Researchers hope the new model will facilitate new avenues of research for ASD.

Featured Neuroscience

·May 5, 2019·4 min read

New chemical probe for visualizing brain immune cells

The chemical probe CDr20 can label microglia in living cells, researchers report.

Brain Cancer Featured Genetics Neuroscience Open Neuroscience Articles

·April 16, 2019·4 min read

Scientists ‘reverse engineer’ brain cancer cells to find new targets for treatment

Using CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.

These are two of the baby clone monkeys.

Featured Genetics Neuroscience Neuroscience Videos Open Neuroscience Articles

·April 11, 2019·5 min read

Gene-edited disease monkeys cloned in China

Researchers in China successfully used CRISPR gene editing to produce five monkey clones from the fibroblasts of a donor monkey with disease phenotypes.

Featured Genetics Neuroscience

·February 25, 2019·2 min read

Manipulating Gene Expression in Neurons with CRISPR

By optimizing neurons with CRISPR gene editing technology, researchers will have new ways to study genetic influences on brain health and disease, a new study reports.