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          CRISPR

          This shows RNA.
          FeaturedGeneticsNeuroscience
          ·July 3, 2023·6 min read

          AI Predicts CRISPR’s RNA-Targeting Effects, Revolutionizing Gene Therapy

          Researchers developed a deep learning model, TIGER, that accurately predicts on- and off-target activity of RNA-targeting CRISPR tools. This new approach allows the fine-tuning of gene activity in human cells.
          Read More
          This shows retinal cells
          FeaturedGeneticsNeuroscienceVisual Neuroscience
          ·March 17, 2023·3 min read

          CRISPR Gene-Editing Technique Reverses Vision Loss in Mice

          Using a highly versatile form of CRISPR gene editing, researchers successfully restored vision in mice with retinitis pigmentosa.
          Read More
          This shows the outline of a head
          FeaturedGeneticsNeurologyNeuroscience
          ·January 30, 2023·5 min read

          How Our Brains Turn Into Smarter Disease Fighters

          CRISPR gene editing created the G795A amino acid which was introduced to microglia derived from human stem cells. Researchers were able to transplant the donor microglia immune cells into humanized rodent models while administering an FDA-approved cancer drug called pexidartinib. The inclusion of the amino acid cause the donated microglia to thrive and resist the drug, while the host microglia died. The findings open the door for new methods of using microglia to treat a range of neurodegenerative disorders.
          Read More
          This shows heart shaped wind chimes
          FeaturedNeuroscience
          ·January 27, 2023·6 min read

          Fresh Questions About Oxytocin as the ‘Love Hormone’ Behind Pair Bonding

          The "love hormone" oxytocin may not play as critical a role in bonding as previously believed. Removing the oxytocin receptor in animal models still resulted in monogamous mating, attachment, and parental bonding behaviors, although females without the receptor produced milk in smaller quantities. Findings reveal parenting and bonding aren't purely dictated by oxytocin receptors.
          Read More
          This shows a brain
          FeaturedGeneticsNeurologyNeuroscience
          ·January 20, 2023·4 min read

          New Nanoparticles Deliver Therapy Brain-Wide and Edit Alzheimer’s Gene

          Researchers have developed a new family of nano-scale capsules capable of carrying CRISPR gene editing tools to different organs of the body before harmlessly dissolving. The capsules were able to enter the brains of mice and successfully edit a gene associated with Alzheimer's disease.
          Read More
          This shows a diagram from the study
          Brain CancerFeaturedNeurologyNeuroscience
          ·January 4, 2023·4 min read

          Cancer Vaccine to Simultaneously Kill and Prevent Brain Cancer Developed

          A new stem cell therapy approach eliminates established brain tumors and provides long-term immunity, training the immune system to prevent cancer from returning.
          Read More
          This shows neurons
          FeaturedGeneticsNeurologyNeuroscience
          ·December 12, 2022·4 min read

          CRISPR Technology Improves Huntington’s Disease Symptoms in Models

          Using CRISPR gene editing to directly target RNA, researchers eliminated toxic protein buildup associated with Huntington's disease while not disrupting other human genes.
          Read More
          This shows the outline of two heads
          FeaturedNeurologyNeuroscience
          ·August 14, 2022·5 min read

          Reprogramming the Brain’s Cleaning Crew to Mop Up Alzheimer’s Disease

          Using CRISPR gene editing, researchers were able to control microglia and reverse their toxic state associated with Alzheimer's disease, and put them back on track.
          Read More
          This shows a sleeping woman
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·April 29, 2022·3 min read

          Clues Into a Sleep Mystery

          Using gene editing to disrupt a gene in the thalamus that codes for a protein that binds to GABA boosted the activity of delta waves and promoted deep sleep in mouse models.
          Read More
          This shows a little girl playing with building blocks
          AutismFeaturedGeneticsNeuroscience
          ·December 13, 2021·5 min read

          New Hope for People Living With a Genetic Cause of Autism

          Gene editing may provide hope for the treatment of Fragile X, the leading genetic cause of autism.
          Read More
          This shows a brain
          FeaturedNeurologyNeuroscience
          ·December 3, 2021·4 min read

          Unique Brain Channel Combats Epileptic Seizures

          The dSlo2 channel appears to play a role in suppressing hyperactivity in the brain that causes epileptic seizures.
          Read More
          This shows a woman and a brain
          FeaturedGeneticsNeuroscience
          ·October 14, 2021·6 min read

          Scientists Map Brain Circuit That Drives Activity in Fertile Females

          Mouse study identifies specific neurons and a signaling pathway to regions of the hindbrain that mediate sexual reproductive activity and physical activity that appear to influence activity behaviors during ovulation. The findings may provide valuable insights into how estrogen loss during menopause disrupts this activity.
          Read More
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          • Hidden in the Hippocampus are the Neural Secrets Behind False Memories
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          Neuroscience News LogoNeuroscience News
          This shows an older man.

          Chronic Stress and Depression Linked to Alzheimer’s Risk

          This shows two young children playing with blocks.

          Playful Brains: Early Years Play Shapes Children’s Futures

          This shows a woman sleeping.

          Sleep Struggles Link to Elevated Risk of Hypertension

          This shows a woman talking to her therapist.

          MDMA Makes People Feel More Connected During Conversations

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