Using CRISPR gene editing, researchers were able to control microglia and reverse their toxic state associated with Alzheimer's disease, and put them back on track.
Using gene editing to disrupt a gene in the thalamus that codes for a protein that binds to GABA boosted the activity of delta waves and promoted deep sleep in mouse models.
Gene editing may provide hope for the treatment of Fragile X, the leading genetic cause of autism.
The dSlo2 channel appears to play a role in suppressing hyperactivity in the brain that causes epileptic seizures.
Mouse study identifies specific neurons and a signaling pathway to regions of the hindbrain that mediate sexual reproductive activity and physical activity that appear to influence activity behaviors during ovulation. The findings may provide valuable insights into how estrogen loss during menopause disrupts this activity.
Researchers have identified specific proteins that drive the development of cancer stem cells. They report targeting and suppressing galectin1, in addition to radiation therapy, could be an effective treatment for glioblastoma brain cancer.
A new study is set to discover precisely which aspects of social behavior androgens regulate and how they do it.
People are less averse to the use of CRISPR gene editing in agriculture if the technology is used to promote disease resistance in animals. However, people tend to dislike the use of CRISPR when it comes to new breeding methods.
CRISPR gene-editing technology allowed researchers to pinpoint specific neurons and mechanisms related to the effects of oxidative stress in the brain.
PLCG2-P522R, a genetic variant that protects against Alzheimer's disease, enhances key functions of immune cells.
Study reveals how a neuropeptide called Big Dynorphin binds to the acid-sensing ion channel receptor, causing pain signals to be sent around the body.
Study identifies a short gene segment crucial for brain development and information processing. The absence of the gene segment induces altered social behaviors, learning difficulties, and memory deficits, which are hallmarks of a subset of ASD.
