A new study funded by the NIMH suggests GLYX-13, a molecular cousin to ketamine, induces similar antidepressant results without the negative side effects of the well known street drug. Read More
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Researchers identify a protein that appears to be the target of both antidepressant drugs and electroconvulsive therapy. The experimental results explain how these therapies likely work to relieve depression by stimulating stem cells in the brain to grow and mature. Read More
Neuroscientists found that astrocytes may be responsible for the rapid improvement in mood in depressed patients after acute sleep deprivation. This study identified how astrocytes can regulate a neurotransmitter involved in sleep. Read More
Scientists have laid bare a novel molecular mechanism responsible for the major depression symptom, anhedonia, the loss of the ability to experience pleasure. The brain circuit involved in this newly elucidated pathway is largely identical between rodents and humans, upping the odds that the findings point toward new therapies for depression and other disorders. Additionally, opinion leaders hailed the study’s inventive methodology, saying it may offer a much sounder approach to testing new antidepressants. Read More
Southwestern Medical Center investigators have identified a genetic manipulation that increases the development of neurons in the brain during aging... Read More
Antidepressant use has been linked to thicker arteries, possibly contributing to the risk of heart disease and stroke, in a... Read More
