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amyloid plaques

The image shows two different brain slices, one of a healthy brain and one of a brain with severe AD.

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·August 2, 2013·4 min read

New Drugs to Find the Right Target to Fight Alzheimer’s Disease

Researchers reveal how two classes of drug compounds, which are currently in trial, work to fight Alzheimer's disease. They also identify possible causes of early onset hereditary forms of AD.

The brain diagram highlights the temporal lobe in yellow.

Featured Neurology

·July 15, 2013·4 min read

Path of Plaque Buildup in Brain Shows Promise as Early Biomarker for Alzheimer’s Disease

Researchers discover early accumulation of amyloid plaques in the temporal lobe is associated with cognitive decline. The finding could serve as a new biomarker for the early detection of Alzheimer's disease.

The diagram shows beta amyloid formation in alzheimer's disease.

Featured Neurology

·June 12, 2013·4 min read

Alzheimer’s Brain Change Measured in Humans

Researchers have successfully measured a significant difference between the brains of patients with an inherited form of Alzheimer's disease and their healthy family members who do not carry the genetic mutation for the disease.

The image which shows how enzymes act on Amyloid precursor protein.

Featured Neuroscience

·May 23, 2013·3 min read

Anti-Cancer Drug Viewed as Possible Alzheimer’s Treatment Doesn’t Work in UF Study

Bexarotene, an anti-cancer drug which is about to be tested in a clinical trial as a potential treatment for Alzheimer's disease, fails to reduce amyloid plagues; according to researchers replicating the original study.

The image shows the amyloid fibril proteins discussed in the article.

Featured Neurology

·May 20, 2013·4 min read

Molecular Trigger for Alzheimer’s Disease Identified

A new study has pinpointed a catalytic trigger for the onset of Alzheimer's disease. The findings could play a central role in the diagnostics and new drug development for neurodegenerative diseases.

The image shows 3 PET scans of patients in different stages of Alzheimer's disease.

Featured Neurology

·May 14, 2013·3 min read

Alzheimer’s Markers Predict Start of Mental Decline

Researchers have identified biomarkers for Alzheimer's disease which accurately predict the development of the disease years prior to symptoms developing.

This is a histopathogic image of senile plaques seen in the cerebral cortex in a patient with presenile onset of Alzheimer disease.

Featured Neuroscience

·March 5, 2013·2 min read

Green Tea Extract Interferes with the Formation of Amyloid Plaques in Alzheimers Disease

Researchers used a specific molecule in green tea extract, EGCG, to control metal associated amyloid beta aggregates associated with Alzheimer's disease and other neurodegenerative disorders.

The image shows 3 diagrams of beta amyloid plaque formations.

Featured Neurology

·February 27, 2013·2 min read

Researchers Identify Possible Treatment Window for Memory Problems

A new study identifies a potential treatment window of several years for plaques in the brain considered to cause memory loss in diseases such as Alzheimer's.

The image shows amyloid plaques in a mouse's hippocampus. The caption best explains the image.

Featured Neurology

·February 5, 2013·5 min read

Damaged Blood Vessels Loaded with Amyloid Worsen Cognitive Impairment in Alzheimer’s Disease

Researchers have discovered that amyloid peptides are harmful to the blood vessels that supply the brain with blood in Alzheimer's disease, thus accelerating cognitive decline by limiting oxygen-rich blood and nutrients.

Cultured cells are shown and described in the caption.

Featured Neuroscience

·January 29, 2013·5 min read

A Better Way to Culture Central Nervous Cells

A protein associated with neuron damage in Alzheimer's patients provides a superior scaffold for growing central nervous system cells in the lab.

Featured Neurology

·October 22, 2012·3 min read

Clue to Alzheimer’s Cause Found in Brain Samples

Researchers found a key difference in the brains of people with Alzheimer’s disease and those who are cognitively normal but still have brain plaques that characterize this type of dementia.