Study provides experimental evidence of an alternative binding site on amyloid-beta aggregates. The discovery opens the door to the development of new therapies for Alzheimer's disease.
Amyloid accumulation occurs faster in those who have objectively-defined cognitive difficulties than older people who are considered to be cognitively normal. Mild cognitive impairment is also associated with faster hippocampal and entorhinal cortex atrophy.
A new study has pinpointed a catalytic trigger for the onset of Alzheimer's disease. The findings could play a central role in the diagnostics and new drug development for neurodegenerative diseases.
Study reports elevated amyloid plaque are not just a risk factor for Alzheimer's, but part of the disease and the earliest precursor before symptoms appear.
Two common compounds, green tea catechins and resveratrol, a compound found in red wine, reduce the formation of Alzheimer's-associated amyloid plaques in brain tissue.
Researchers discover early accumulation of amyloid plaques in the temporal lobe is associated with cognitive decline. The finding could serve as a new biomarker for the early detection of Alzheimer's disease.
A new study reports amyloid plaques are present shortly after brain injury in middle aged people. The findings may help explain why people who suffer TBIs are at an increased risk for developing Alzheimer's.
A newly developed antibody has shown to trigger a meaningful reduction of amyloid beta in patients with early stage Alzheimer's disease.
Researchers map a toxic protein associated with Alzheimer's disease. The study reports that pS8-AB40 acts as the alpha structure in polymorphism and has higher levels of cellular toxicity compared to other fibrils.
Researchers uncover a second rare genetic mutation which increases the risk of developing Alzheimer's disease later in life.
Subtle changes in thinking and memory may appear before, or in conjunction with, the development of amyloid plaques.
Researchers report they have discovered the mechanism that leads to the rapid build up of amyloid plaques in Alzheimer's disease.
