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Alzheimer’s disease

Featured Neurology Open Neuroscience Articles

·June 26, 2013·6 min read

Promising Alzheimer’s ‘Drug’ Halts Memory Loss

Researchers discover a new class of experimental drug like small molecules show promise in targeting a brain enzyme to prevent early memory loss in Alzheimer's disease.

The image shows neurofibrillary tangles associated with Alzheimer's.

Featured Neurology

·June 26, 2013·3 min read

Alzheimer’s Disease Mouse Models Point To A Potential Therapeutic Approach

Using well known mouse models, researchers demonstrate a potential new target to fight Alzheimer's and other neurodegenerative diseases.

The image shows a diagram of neurons and an insert which shows how a synapse works.

Featured Neurology

·June 25, 2013·3 min read

Protein Linked to Cognitive Decline in Alzheimer’s Identified

Caspase-2 is a key regulator of a signaling pathway which leads to cognitive decline in Alzheimer's disease, a new study finds.

The image shows the s1 of a mouse cerebral cortex.

Featured Neuroscience

·June 25, 2013·3 min read

Problem-Solving Governs How We Process Sensory Stimuli

Researchers demonstrate how the transmission of sensory information from one cortical area to connected areas depends on the specific task at hand and goal directed behavior.

Featured Neuroscience

·June 24, 2013·4 min read

NMR Advance Brings Proteins into the Open

Researchers combine data from four different NMR techniques to observe chaperone GroEL capture a disordered beta-amyloid protein.

The image shows PET scans of a person's brain with Alzheimer's disease.

Featured Neurology

·June 21, 2013·3 min read

Alzheimer’s Disease Protein Controls Movement in Mice

Researchers reveal the Bace1 protein, well known for its role in Alzheimer's disease, controls spindle development in muscles and leads to impaired movement when absent.

This is a painting of neuronal development.

Featured Neuroscience

·June 20, 2013·4 min read

Scientists Discover Key Signaling Pathway that Makes Young Neurons Connect

Researchers have identified a molecular program which spurs the growth of neuronal output connections.

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·June 20, 2013·2 min read

“Forrest Gump” Mice Show Too Much of a Good Thing Can be Bad

Using a line of genetically modified mice, researchers discover boosting acetylcholine can disturb cognitive function.

The image shows the tau proteins associated with Alzheimer's disease.

Featured Neurology

·June 19, 2013·3 min read

New Alzheimer’s Research Suggests Possible Cause: The Interaction of Proteins in the Brain

Researchers discover by looking at amyloid-beta and tau independently that the interaction between the proteins could be the key to the cognitive decline associated with Alzheimer's disease. As the interaction between the two proteins increased, the progression of Alzheimer's worsened.

Diagram illustrating the influence of dark-light rhythms on circadian rhythms and related physiology and behavior.

Featured Neuroscience

·June 18, 2013·4 min read

Key Protein is Linked to Circadian Clocks, Helps Regulate Metabolism

A new study reveals how the production of p75NTR protein oscillates in time with the body's natural circadian rhythm and how these oscillations help regulate vital metabolic functions. The findings offer an insight into how circadian rhythm helps maintain the body's overall metabolic health.

This is a horizontal slice of the head of an adult female.

Featured Neurology

·June 18, 2013·3 min read

Concussion Patients Show Alzheimer’s-Like Brain Abnormalities

A new study has discovered the distribution of white matter abnormalities found in some patients with mTBI closely resemble those seen in early Alzheimer's disease.

The image shows an electrophysiology slide of neurons in this alzheimer's research.

Featured Neurology

·June 17, 2013·2 min read

Blocking Overactive Receptor in Alzheimer’s Recovers Memory Loss and More

Researchers show memory pathology in older mice can be reversed by blocking the activity of a specific receptor in the brain. Blocking the B1R receptor helps recover memory and cerebrovascular function.