Neuroscience research articles are provided.
What is neuroscience? Neuroscience is the scientific study of nervous systems. Neuroscience can involve research from many branches of science including those involving neurology, brain science, neurobiology, psychology, computer science, artificial intelligence, statistics, prosthetics, neuroimaging, engineering, medicine, physics, mathematics, pharmacology, electrophysiology, biology, robotics and technology.
– These articles focus mainly on neurology research. – What is neurology? – Definition of neurology: a science involved in the study of the nervous systems, especially of the diseases and disorders affecting them. – Neurology research can include information involving brain research, neurological disorders, medicine, brain cancer, peripheral nervous systems, central nervous systems, nerve damage, brain tumors, seizures, neurosurgery, electrophysiology, BMI, brain injuries, paralysis and spinal cord treatments.
What is Psychology? Definition of Psychology: Psychology is the study of behavior in an individual, or group. Psychology news articles are listed below.
Artificial Intelligence articles involve programming, neural engineering, artificial neural networks, artificial life, a-life, floyds, boids, emergence, machine learning, neuralbots, neuralrobotics, computational neuroscience and more involving A.I. research.
Robotics articles will cover robotics research press releases. Robotics news from universities, labs, researchers, engineers, students, high schools, conventions, competitions and more are posted and welcome.
Genetics articles related to neuroscience research will be listed here.
Neurotechnology research articles deal with robotics, AI, deep learning, machine learning, Brain Computer Interfaces, neuroprosthetics, neural implants and more. Read the latest neurotech news articles below.
Summary: According to a new study, clinically depressed children show a blunted response to reward compared to those who were not depressed.
Brains react less robustly to success, rewards.
For many children, December often is linked to presents and excitement, but when a young child doesn’t seem all that enthused about getting gifts, it could be a sign that something is wrong. Measuring brain waves, researchers at Washington University School of Medicine in St. Louis have found that clinically depressed children don’t respond to rewards the same way as other children do.
Previous research from the same group of scientists found that a reduced ability to experience joy is a key sign of clinical depression in young children. The findings in the new study could help explain the biological underpinnings of the earlier discovery.
“These findings may show us how the brain processes emotions in young children with depression,” said senior investigator Joan L. Luby, MD, director of Washington University’s Early Emotional Development Program. “The pleasure we derive from rewards — such as toys and gifts — motivates us to succeed and seek more rewards. Dampening the process early in development is a serious concern because it may carry over to how a person will approach rewarding tasks later in life.”
The new findings are published in the December 2016 issue of the Journal of the American Academy of Child & Adolescent Psychiatry.
“A blunted response to reward frequently is seen in the brains of depressed adults and adolescents,” said first author Andrew C. Belden, PhD, an assistant professor of child psychiatry. “In this study, we were interested in learning whether preschoolers also had that blunted response to reward, and in fact, the brains of children as young as 4 showed very similar responses. That’s consistent with other findings in that many neurobehavioral aspects of depression remain consistent throughout the lifespan.”
The research, involving 84 children, was conducted as part of a larger study of clinical depression in children ages 3 to 7. The principal investigators of that larger study, which includes therapy and functional brain scanning, are Luby and Deanna M. Barch, PhD, chair of Washington University’s Department of Psychological & Brain Sciences in Arts & Sciences and the Gregory B. Couch Professor of Psychiatry at the School of Medicine.
The children wore a device that resembles a shower cap but is hooked to wires that measure electrical activity in the brain using an electroencephalogram machine (EEG). Then, the children played a computer game that involved choosing between two doors shown on the screen. Choosing one door won them points, but choosing the other resulted in a loss of points.
Researchers have tested this idea in adults and teens by allowing them to win cash. In this study, however, young children who picked the correct door enough times won a toy that they were able to pick from a basket of figures, balls and plush items they had been shown before the computer session began.
While the brains of clinically depressed children responded similarly to those of nondepressed children when points were lost, the response when the correct door was chosen was blunted.
“The EEG results showed that their brains did not react as robustly from the pleasurable event of choosing the correct door on the screen,” Belden said. “It was not that their brains somehow overreacted to making the wrong choice. The brains of both depressed and nondepressed children reacted the same way to making the wrong choice. The differences we observed were specific to the reward response.”
Luby and Belden next plan to see whether the blunted response to reward changes after treatment.
“It may or may not normalize,” said Luby, the Samuel and Mae S. Ludwig Professor of Child Psychiatry. “But we suspect the reward response will improve.”
Luby and Belden said that when a very young child doesn’t seem to be excited by rewards, such as toys and gifts, it may be a sign that the child is depressed or prone to depression. If the condition persists, they suggest parents talk to a pediatrician.
“There are clear risk factors,” Luby explained. “Decreased ability to enjoy activities and play is a key sign. Kids who feel excessively guilty about wrongdoing and those who experience changes in sleep and appetite also may be at risk. If they’re persistently sad, irritable or less motivated, those are markers that may indicate depression, even in kids as young as 3 or 4, and we would recommend that parents get them evaluated.”
[divider]About this psychology research article[/divider]
Funding: This work was supported by the National Institute of Mental Health of the National Institutes of Health (NIH), grant numbers 1R01 MH098454-01A1 and 3R01 MH098454-03S1.
Dr. Luby has received royalties from Guilford Press. Dr. Barch has served as a consultant for Pfizer, Amgen, Roche and Takeda and has a contract to analyze imaging date from Pfizer.
Source: Jim Dryden – WUSTL Image Source: NeuroscienceNews.com image is credited to Robert Boston. Original Research: Abstract for “Neural correlates of reward processing in depressed and healthy preschool-age children” by Belden AC, Irgin K, Hajcak G, Kappenman ES, Kelly D, Karlow S, Luby JL, and Barch DM in Journal of the American Academy of Child & Adolescent Psychiatry. Published online October 4 2016 doi:10.1016/j.jaac.2016.09.503
[divider]Cite This NeuroscienceNews.com Article[/divider]
[cbtabs][cbtab title=”MLA”]WUSTL. “Depressed Children Respond Differently to Rewards Than Other Kids.” NeuroscienceNews. NeuroscienceNews, 15 December 2016. <https://neurosciencenews.com/reward-teen-depression-5753/>.[/cbtab][cbtab title=”APA”]WUSTL. (2016, December 15). Depressed Children Respond Differently to Rewards Than Other Kids. NeuroscienceNews. Retrieved December 15, 2016 from https://neurosciencenews.com/reward-teen-depression-5753/[/cbtab][cbtab title=”Chicago”]WUSTL. “Depressed Children Respond Differently to Rewards Than Other Kids.” https://neurosciencenews.com/reward-teen-depression-5753/ (accessed December 15, 2016).[/cbtab][/cbtabs]
Neural correlates of reward processing in depressed and healthy preschool-age children
Objective Adults and adolescents with major depressive disorder (MDD) show a blunted neural response to rewards. Depression has been validated in children as young as age 3; however, it remains unclear whether blunted response to reward is also a core feature of preschool-onset depression. If so, this would provide further validation for the continuity of the neural correlates of depression across the life span and would identify a potential target for treatment in young children.
Method Fifty-three 4- to 7-year-old children with depression and 25 psychiatrically healthy 4- to 7-year-old children completed a simple guessing task in which points could be won or lost on each trial while event-related potentials (ERPs) were recorded. Psychiatric diagnosis was established using a preschool version of the Kiddie Schedule for Affective Disorders and Depression.
Results Young children with depression showed a reduced differentiation between response to gains and losses, and this finding was driven by a blunted response to reward (i.e., the reward positivity [RewP]). These findings held even when controlling for co-occurring attention-deficit/hyperactivity disorder, oppositional defiant disorder, and generalized anxiety disorder. The RewP did not vary as a function of depression severity within the group with depression.
Conclusion Similar to adults and adolescents with depression, preschoolers with depression display reductions in responsivity to rewards as indexed by the RewP. These findings provide further evidence for continuity in the neural mechanisms associated with depression across the lifespan, and point to altered reward sensitivity as an early-emerging potential target for intervention in preschool-onset depression.
“Neural correlates of reward processing in depressed and healthy preschool-age children” by Belden AC, Irgin K, Hajcak G, Kappenman ES, Kelly D, Karlow S, Luby JL, and Barch DM in Journal of the American Academy of Child & Adolescent Psychiatry. Published online October 4 2016 doi:10.1016/j.jaac.2016.09.503
[divider]Feel free to share this Neuroscience News.[/divider]