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Pain Neuroscience news articles cover science research about pain receptors, nociceptors, nociception, sensory neurons, somatosensory cortex, chronic pain, acute pain, nocioceptors, musculoskeletal pain, therapies, phantom limb pain and other pain research.

These brain scans shows the foot area highlighted

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·July 17, 2019·3 min read

Hit it where it hurts: Scientists reveal how mirrors cure phantom pain

Visual responsiveness in the somatosensory cortex diminishes significantly following mirror therapy for phantom limb pain. Before therapy, researchers discovered a strong, unexpected activation in the sensorimotor foot region of amputees to visually presented images of the foot. This response was no longer present following mirror therapy.

This shows potassium channels on neurons

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·July 15, 2019·3 min read

Defective potassium channels cause headache, not body pain

The loss of TRESK significantly increases the risk of developing headaches and may be implicated in migraines.

$This shows a cross section of the spinal cord$

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·July 11, 2019·4 min read

Mathematical Model Explores Daily Rhythms in Pain Sensitivity

A new mathematical model can accurately reproduce experimental results on pain sensitivity and predict how the results are affected by the time of day.

This shows a woman crossing her legs while someone else touches her foot

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·June 14, 2019·6 min read

Phantom sensations: When the sense of touch deceives

Healthy individuals some times misattribute tactile stimulation to the wrong side, and even wrong parts, of their body. This is especially true if the part of the body is crossed, where the left hand is positioned on the right, for example. Findings shed new light on the way in which the brain represents the body.

Featured Neurology Neuroscience Pain

·June 11, 2019·3 min read

Promising treatment option for Complex Regional Pain Syndrome

Blocking the activity of interleukin-1 in mouse models of complex regional pain syndrome (CRPS) helped reverse symptoms. Researchers say patients with CRPS should respond to immune-based treatments which reduce some of the disease features.

This shows an alarm clock against a multi-colored background

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·June 4, 2019·5 min read

Opioids are not sleep aids, and can actually worsen sleep research finds

Opioids are often prescribed to help those with chronic pain manage sleep problems associated with their condition. New research reports opioids effect on sleep quality is limited and of poor quality. Additionally, opioids can increase the risk of sleep apnea.

This shows the prefrontal cortex in the brain

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·May 21, 2019·2 min read

Multiple brain regions moderate and link depressive mood and pain

People with higher levels of depressive moods exhibited heightened sensitivity to pain, and had greater activation in the prefrontal cortex, insula and somatosensory cortex.

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·May 16, 2019·2 min read

The insular cortex processes, and drives learning from pain

Using optogenetics to 'switch off' the insular cortex in mice experiencing a painful event resulted in a less fearful reaction to pain. The ability of the mice to learn avoidance from the pain event was also reduced.

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·May 14, 2019·4 min read

Common antibiotic may increase nerve damage and peripheral neuropathy risk

Fluoroquinolone antibiotics, such as Levofloxacin and Ciprofloxacin, appear to increase the risk of peripheral neuropathy by 47%. However, there is no significant increased risk of developing neuropathy associated with amoxicillin use.

This shows an outline of a person with a red brain

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·May 7, 2019·4 min read

Does insulin resistance cause fibromyalgia?

Study finds a pathogenic relationship between insulin resistance and fibromyalgia. Treating fibromyalgia with metformin, a drug that combats insulin resistance, resulted in a dramatic reduction of pain levels for patients.

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·April 29, 2019·4 min read

Newfound autoimmune syndrome causes muscle pain, weakness

Researchers have identified a new autoimmune disease that causes muscle pain and weakness. Large-histiocyte-related immune myopathy (LHIM), generates similar results to the condition rhabdomyolysis in blood chemistry samples. LHIM can effectively be treated with anti-inflammatory drugs to help reduce symptoms.

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·April 8, 2019·5 min read

Migraine-linked protein exhibits sex-specific pain effects

CGRP, a protein associated with migraine pain, appears to act differently between sexes. Researchers say a female-specific mechanism of downstream CGRP receptor activation is likely to contribute to the higher prevalence of migraine in women.