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Genetics

Genetics articles related to neuroscience research will be listed here.

This is the chemical structure of FKBP51

Featured Genetics Neurology Neuroscience Psychology

·April 1, 2019·3 min read

Depression, obesity, chronic pain could be treated by targeting the same key protein

Researchers have developed a compound that blocks the FKBP51 protein, which helps reduce chronic pain, provides positive outcomes for diet-induced obesity and improves symptoms of depression.

Featured Genetics Neuroscience Psychology

·March 31, 2019·3 min read

30 Genes Associated with Schizophrenia Identified

A new phenotype atlas assisted researchers in identifying 30 genes associated with an increased risk of developing schizophrenia. Single-cell RNA sequencing revealed an essential role for the transcription factor znf536 in the development of forebrain neurons associated with social behavior and stress.

Three people are shown in the picture with a building in the background.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles Pain

·March 29, 2019·5 min read

Woman with novel gene mutation lives almost pain-free

A rare genetic mutation has been associated with pain insensitivity. The findings could further research into new treatments to target pain.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·March 29, 2019·5 min read

Researchers discover two, rare genes associated with Alzheimer’s disease

Two rare genetic variants on the NOTCH3 and TREM2 genes have been identified in some Alzheimer's patients.

Featured Genetics Neuroscience

·March 28, 2019·3 min read

Single Population of Stem Cells Contributes to Lifelong Hippocampal Neurogenesis: Mouse Study

The findings support a continuous model of neurogenesis throughout development and adulthood.

Featured Genetics Neuroscience Psychology

·March 22, 2019·4 min read

When neurons are out of shape, antidepressants may not work

Differences in serotonergic neuron morphology, along with altered gene expression have been identified in patients with MDD. The findings shed light on why some patients do not respond to SSRI antidepressants.

Featured Genetics Neuroscience Open Neuroscience Articles Visual Neuroscience

·March 17, 2019·8 min read

With single gene insertion, blind mice regain sight

Gene therapy that targets retinal ganglion cells with light-sensitive cone opsins helps restore vision in mice. Researchers report a potential human treatment could be available within three years.

Featured Genetics Neuroscience

·March 14, 2019·5 min read

Serotonin Can Directly Regulate Gene Expression Inside Brain Cells

Serotonin can chemically attach to histone proteins in the cell nucleus to help regulate gene expression. The findings may provide a better understanding of an array of psychological disorders and neurodegenerative diseases.

Featured Genetics Psychology

·March 13, 2019·4 min read

NIH-funded rodent study finds molecular link between adolescent alcohol use and adult anxiety

Adolescent rats exposed to alcohol had a decrease of both Arc eRNA expression and Arc gene expression in the amygdala during adulthood. Additionally, the alcohol-exposed rats displayed increased anxiety behaviors as they aged.

Featured Genetics Neuroscience Open Neuroscience Articles

·March 13, 2019·4 min read

New Cell Subtypes Classified in Mouse Brain

A new process for classifying neurons in the brains of mice has been outlined by researchers from Cold Spring Harbor Laboratory. The platform pairs microscopy with genetic labeling at single neuron resolution, allowing researchers to reconstruct the brain, by providing information on every neuronal type's location.

Featured Genetics Neuroscience Psychology

·March 12, 2019·5 min read

Scientists identify gene that keeps PTSD-like behavior at bay in female mice

A new study reveals how a prion-like protein that is encoded by the TIA1 gene helps to regulate fear memories. TIA1, researchers report, may be a promising new target for the treatment of PTSD.