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TREM2

Featured Neurology

·December 14, 2016·4 min read

Early Signs of Alzheimer’s Detected in Cerebrospinal Fluid

Researchers have discovered an early immune response in people with a genetic predisposition to Alzheimer's disease.

Featured Genetics Neurology Open Neuroscience Articles

·July 21, 2016·4 min read

Three Alzheimer’s Genetic Risk Factors Linked to Immune Cell Dysfunction

Researchers report the TREM2 mutation can derail the immune cell's plaque-clearing activity.

Image shows amyloid beta attacking a cell.

Featured Neurology

·June 15, 2016·8 min read

A New Role For Amyloid Beta in Alzheimer’s

Researchers have developed a new technique to measure levels of amyloid beta in the brain. They have also discovered new insights into why mutations of the TREM2 gene increases the risk of developing Alzheimer's disease.

Featured Neurology

·May 19, 2016·3 min read

Immune Cells May Protect Against Alzheimer’s

Researchers report microglia may actually protect the brain against Alzheimer's disease by containing the spread of amyloid plaques.

Featured Neurology Open Neuroscience Articles

·March 7, 2016·3 min read

Does A ‘Western Diet’ Increase Alzheimer’s Risk?

Having a sedentary lifestyle and eating a western diet is linked to an increased risk of developing Alzheimer's disease, a new study reports.

Diagram shows how TREM2 attaches to neurons.

Featured Neurology Open Neuroscience Articles

·March 5, 2016·5 min read

Early Biomarkers for Alzheimer’s Defined

Researchers have identified a biomarker that is associated with the activation of an innate immune response to neural damage during the early stages of Alzheimer's disease.

Image of a normal brain slice and a brain slice of an Alzheimer's patient.

Featured Genetics Neurology

·September 28, 2015·4 min read

Possible Role of Immune System in Onset of Alzheimer’s Disease

A new study investigates how genetics risk factors for Alzheimer's could influence a key immune cell.

This image shows normal microglia (red) surround Alzheimer's plaques.

Featured Genetics Neurology

·March 2, 2015·4 min read

New Genetic Target Identified in Fight Against Some Neurodegenerative Diseases

According to a new study, triggering TREM2 could help slow the progression of some neurodegenerative diseases.

This is a histopathogic image of senile plaques seen in the cerebral cortex in a patient with presenile onset of Alzheimer disease.

Featured Genetics

·December 13, 2013·5 min read

New Gene Discovery Sheds More Light on Alzheimer’s Risk

Researchers uncover a second rare genetic mutation which increases the risk of developing Alzheimer's disease later in life.

The image is a drawing of a brain slice with alzheimer's disease.

Featured Genetics

·October 27, 2013·6 min read

Study Identifies 11 New Alzheimer’s Disease Risk Genes

Researchers have identified 11 new genes which offer important new insights into the disease pathways associated with Alzheimer's disease.

the image shows an MRI scan of an Alzheimer's patient who carries the TERM2 genetic mutation.

Featured Genetics

·October 18, 2013·3 min read

Genetic Mutation Linked to Alzheimer’s Disease Doubles Rate of Brain Tissue Loss

Carries of the TREM2 genetic mutation associated with Alzheimer's disease could develop the disease up to three years earlier than expected, a new study finds.